A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
Abstract Motivation: The Illumina Infinium 450 k DNA Methylation Beadchip is a prime
candidate technology for Epigenome-Wide Association Studies (EWAS). However, a …
candidate technology for Epigenome-Wide Association Studies (EWAS). However, a …
RCP: a novel probe design bias correction method for Illumina Methylation BeadChip
Abstract Motivation: The Illumina HumanMethylation450 BeadChip has been extensively
utilized in epigenome-wide association studies. This array and its successor, the …
utilized in epigenome-wide association studies. This array and its successor, the …
[HTML][HTML] Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip
Genome-wide analysis of DNA methylation has now become a relatively inexpensive
technique thanks to array-based methylation profiling technologies. The recently developed …
technique thanks to array-based methylation profiling technologies. The recently developed …
RELIC: a novel dye-bias correction method for Illumina Methylation BeadChip
Abstract Background The Illumina Infinium HumanMethylation450 BeadChip and its
successor, Infinium MethylationEPIC BeadChip, have been extensively utilized in …
successor, Infinium MethylationEPIC BeadChip, have been extensively utilized in …
Meffil: efficient normalization and analysis of very large DNA methylation datasets
Motivation DNA methylation datasets are growing ever larger both in sample size and
genome coverage. Novel computational solutions are required to efficiently handle these …
genome coverage. Novel computational solutions are required to efficiently handle these …
ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip
Abstract The Illumina HumanMethylation450 BeadChip is increasingly utilized in epigenome-
wide association studies, however, this array-based measurement of DNA methylation is …
wide association studies, however, this array-based measurement of DNA methylation is …
SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips
DNA methylation is the most widely studied epigenetic mark and is known to be essential to
normal development and frequently disrupted in disease. The Illumina …
normal development and frequently disrupted in disease. The Illumina …
Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies
AE Teschendorff, J Zhuang, M Widschwendter - Bioinformatics, 2011 - academic.oup.com
Motivation: A common difficulty in large-scale microarray studies is the presence of
confounding factors, which may significantly skew estimates of statistical significance, cause …
confounding factors, which may significantly skew estimates of statistical significance, cause …
Low-level processing of Illumina Infinium DNA methylation beadarrays
TJ Triche Jr, DJ Weisenberger… - Nucleic acids …, 2013 - academic.oup.com
We propose a novel approach to background correction for Infinium HumanMethylation data
to account for technical variation in background fluorescence signal. Our approach …
to account for technical variation in background fluorescence signal. Our approach …
A framework for analyzing DNA methylation data from Illumina Infinium HumanMethylation450 BeadChip
Z Wang, XL Wu, Y Wang - BMC bioinformatics, 2018 - Springer
Background DNA methylation has been identified to be widely associated to complex
diseases. Among biological platforms to profile DNA methylation in human, the Illumina …
diseases. Among biological platforms to profile DNA methylation in human, the Illumina …