We assessed gene expression in tissue macrophages from various mouse organs. The
diversity in gene expression among different populations of macrophages was considerable …

Macrophages are essential components of mammalian tissues. Although historically known
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …

Macrophages provide a critical systemic network cells of the innate immune system.
Emerging data suggest that in addition, they have important tissue-specific functions that …

Macrophages have protective roles in immunity to pathogens, tissue development,
homeostasis and repair following damage. Maladaptive immunity and inflammation provoke …

Monocytes recruited into tissues from peripheral blood differentiate into macrophages, which
are critical in the pathogenesis of many diseases. There is limited data concerning the …

Macrophages, the most plastic cells of the haematopoietic system, are found in all tissues
and show great functional diversity. They have roles in development, homeostasis, tissue …

Macrophages have been at the heart of immune research for over a century and are an
integral component of innate immunity. Macrophages are often viewed as terminally …

Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …

Macrophages are dynamic cells integrating signals from their microenvironment to develop
specific functional responses. Although, microarray-based transcriptional profiling has …

In tissues, macrophages are exposed to metabolic, homeostatic and immunoregulatory
signals of local or systemic origin that influence their basal functions and responses to …