Orbitofrontal dysfunction related to both apathy and disinhibition in frontotemporal dementia

F Peters, D Perani, K Herholz, V Holthoff… - Dementia and geriatric …, 2006 - karger.com
Orbitofrontal metabolic impairment is characteristic of the frontal variant of frontotemporal
dementia (fv-FTD), as are early changes in emotional and social conduct. Two main types of …

Comparative cognitive neuropsychological studies of frontal lobe function: implications for therapeutic strategies in frontal variant frontotemporal dementia

S Rahman, TW Robbins, BJ Sahakian - Dementia and Geriatric …, 1999 - karger.com
Patients with mild frontal variant frontotemporal dementia (fvFTD) who attend the clinic are
usually unaware of the pervasive changes in their personality and behaviour, despite the …

Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementia

E Salmon, G Garraux, X Delbeuck, F Collette, E Kalbe… - Neuroimage, 2003 - Elsevier
In a multicenter study, FDG-PET images in a population of 29 patients with frontotemporal
dementia (FTD) were compared to controls with similar age from each center. A conjunction …

Behavioral disturbances in the course of frontotemporal dementia

J Diehl-Schmid, C Pohl, R Perneczky… - Dementia and geriatric …, 2006 - karger.com
Background: Behavioral disturbances are prominent in frontotemporal dementia (FTD), and
their occurrence has been the topic of several investigations. Nonetheless, the prevalence …

The relationship between affective decision-making and theory of mind in the frontal variant of fronto-temporal dementia

T Torralva, CM Kipps, JR Hodges, L Clark… - Neuropsychologia, 2007 - Elsevier
Structural brain imaging and neuropsychological data implicate the orbital aspects of
prefrontal cortex in the developing neuropathology of fvFTD. Damage to this region is …

Measuring and modifying abnormal social cognition in frontal variant frontotemporal dementia

S Lough, JR Hodges - Journal of psychosomatic research, 2002 - Elsevier
We describe a 57-year-old man (MW) with frontal variant frontotemporal dementia (fv-FTD)
who presented with a long history of drinking problem and marital disharmony followed by …

Functional neuroimaging and presenting psychiatric features in frontotemporal dementia

MF Mendez, A McMurtray, AK Chen… - Journal of Neurology …, 2006 - jnnp.bmj.com
Background: Frontotemporal dementia (FTD) is a behavioural syndrome caused by
degeneration of the frontal and anterior temporal lobes. Behavioural disturbances include …

Patterns of frontal lobe atrophy in frontotemporal dementia: a volumetric MRI study

RJ Perry, A Graham, G Williams, H Rosen… - Dementia and geriatric …, 2006 - karger.com
Abstract Objectives: Frontotemporal dementia (FTD), the second commonest degenerative
cause of dementia under the age of 65, often presents with striking changes in behaviour …

Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer's disease?

S Bozeat, CA Gregory, MAL Ralph… - Journal of Neurology …, 2000 - jnnp.bmj.com
OBJECTIVES To investigate the prevalence of changes in mood, personality, and behaviour
in frontotemporal dementia (FTD) and Alzheimer's disease (AD) and hence, which features …

Alzheimer disease and frontotemporal dementias: behavioral distinctions

ML Levy, BL Miller, JL Cummings… - Archives of …, 1996 - jamanetwork.com
Background: Frontotemporal dementia (FTD) is a syndrome produced by lobar degeneration
of the temporal and/or frontal lobes. Objectives: To quantify the behavioral disturbances of …