[HTML][HTML] Full factorial design for optimization, development and validation of HPLC method to determine valsartan in nanoparticles
High performance liquid chromatographic method was optimized, developed and validated
as per the ICH guidelines. In this study the 20 mM ammonium formate and acetonitrile in the …
as per the ICH guidelines. In this study the 20 mM ammonium formate and acetonitrile in the …
Nanocrystallization by evaporative antisolvent technique for solubility and bioavailability enhancement of telmisartan
A Bajaj, MRP Rao, A Pardeshi, D Sali - AAPS pharmscitech, 2012 - Springer
Telmisartan is an orally active nonpeptide angiotensin II receptor antagonist used in the
management of hypertension. It is a Biopharmaceutics Classification System class II drug …
management of hypertension. It is a Biopharmaceutics Classification System class II drug …
Nanosizing of valsartan by high pressure homogenization to produce dissolution enhanced nanosuspension: pharmacokinetics and pharmacodyanamic study
Purpose: The purpose of the present study was to formulate and evaluate nanosuspension
of Valsartan (VAL), a poorly water soluble and low bioavailable drug (solubility of 0.18 mg …
of Valsartan (VAL), a poorly water soluble and low bioavailable drug (solubility of 0.18 mg …
[HTML][HTML] Simultaneous determination of valsartan and hydrochlorothiazide in tablets by RP-HPLC
DF Tian, XL Tian, T Tian, ZY Wang… - Indian journal of …, 2008 - ncbi.nlm.nih.gov
A simple, reproducible and efficient reverse phase high performance liquid chromatographic
method was developed for simultaneous determination of valsartan and hydrochlorothiazide …
method was developed for simultaneous determination of valsartan and hydrochlorothiazide …
Preparation and statistical optimization of Losartan Potassium loaded nanoparticles using Box Behnken factorial design: Microreactor precipitation
The current study deals with the development and optimization of Losartan Potassium (LP)
loaded nanoparticles by continuous flow microreactor precipitation methodology for …
loaded nanoparticles by continuous flow microreactor precipitation methodology for …
Uniform nano-sized valsartan for dissolution and bioavailability enhancement: influence of particle size and crystalline state
Q Ma, H Sun, E Che, X Zheng, T Jiang, C Sun… - International journal of …, 2013 - Elsevier
The central purpose of this study was to evaluate the impact of drug particle size and
crystalline state on valsartan (VAL) formulations in order to improve its dissolution and …
crystalline state on valsartan (VAL) formulations in order to improve its dissolution and …
Preparation of Candesartan and Atorvastatin Nanoparticles by Solvent Evaporation †
E Vaculikova, V Grunwaldova, V Kral, J Dohnal… - Molecules, 2012 - mdpi.com
The solubility, absorption and distribution of a drug are involved in the basic aspects of oral
bioavailability Solubility is an essential characteristic and influences the efficiency of the …
bioavailability Solubility is an essential characteristic and influences the efficiency of the …
[PDF][PDF] Valsartan loaded solid lipid nanoparticles: development, characterization and in vitro and ex vivo evaluation
B Parmar, S Mandal, KC Petkar, LD Patel… - Int J Pharm Sci …, 2011 - researchgate.net
Valsartan is an antihypertensive drug with poor oral bioavailability ranging from 10-35%
because of poor solubility, dissolution and most importantly, extensive first pass hepatic …
because of poor solubility, dissolution and most importantly, extensive first pass hepatic …
Stability Indicating RP‐HPLC Method for Determination of Valsartan in Pure and Pharmaceutical Formulation
SK Patro, SK Kanungo, VJ Patro… - Journal of …, 2010 - Wiley Online Library
A simple, rapid and accurate and stability indicating RP‐HPLC method was developed for
the determination of valsartan in pure and tablet forms. The method showed a linear …
the determination of valsartan in pure and tablet forms. The method showed a linear …