The mef(A)/msr(D)-carrying streptococcal prophage Φ1207.3 encodes an SOS-like system, induced by UV-C light, responsible for increased survival and increased …

V Fox, F Santoro, C Apicella, S Diaz-Diaz… - Journal of …, 2023 - Am Soc Microbiol
Bacterial SOS response is an inducible system of DNA repair and mutagenesis. Streptococci
lack a canonical SOS response, but an SOS-like response was reported in some species …

Streptococcus pyogenes Φ1207.3 Is a Temperate Bacteriophage Carrying the Macrolide Resistance Gene Pair mef(A)-msr(D) and Capable of Lysogenizing …

F Santoro, G Pastore, V Fox, MA Petit… - Microbiology …, 2023 - Am Soc Microbiol
ABSTRACT Streptococcus pyogenes prophage Φ1207. 3 (formerly Tn 1207.3) carries the
mef (A)-msr (D) resistance genes, responsible for type M macrolide resistance. To …

Phage-associated mutator phenotype in group A streptococcus

J Scott, P Thompson-Mayberry, S Lahmamsi… - Journal of …, 2008 - Am Soc Microbiol
Defects in DNA mismatch repair (MMR) occur frequently in natural populations of
pathogenic and commensal bacteria, resulting in a mutator phenotype. We identified a …

Identification of a Novel Streptococcal Gene Cassette Mediating SOS Mutagenesis in Streptococcus uberis

E Varhimo, K Savijoki, J Jalava, OP Kuipers… - Journal of …, 2007 - Am Soc Microbiol
Streptococci have been considered to lack the classical SOS response, defined by
increased mutation after UV exposure and regulation by LexA. Here we report the …

Φm46.1, the Main Streptococcus pyogenes Element Carrying mef(A) and tet(O) Genes

A Brenciani, A Bacciaglia, C Vignaroli… - Antimicrobial agents …, 2010 - Am Soc Microbiol
ABSTRACT Φm46. 1, the recognized representative of the most common variant of mobile,
prophage-associated genetic elements carrying resistance genes mef (A)(which confers …

[HTML][HTML] Transduction of the Streptococcus pyogenes bacteriophage Φm46.1, carrying resistance genes mef(A) and tet(O), to other Streptococcus species

E Giovanetti, A Brenciani, G Morroni, E Tiberi… - Frontiers in …, 2015 - frontiersin.org
Φm46. 1–Streptococcus pyogenes bacteriophage carrying mef (A) and tet (O), respectively,
encoding resistance to macrolides (M phenotype) and tetracycline–is widespread in S …

Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370

C Venturini, CY Ong, CM Gillen… - Infection and …, 2013 - Am Soc Microbiol
The resurgence of invasive disease caused by Streptococcus pyogenes (group A
Streptococcus [GAS]) in the past 30 years has paralleled the emergence and global …

Introduction of the emm6 gene into an emm-deleted strain of Streptococcus pyogenes restores its ability to resist phagocytosis

J Perez-Casal, MG Caparon, JR Scott - Research in microbiology, 1992 - Elsevier
To complete the formal proof that the M protein functions to protect the group A
streptococcus from phagocytosis and to lay the groundwork for the molecular genetic …

Genetic Resistance Elements Carrying mef Subclasses Other than mef(A) in Streptococcus pyogenes

M Del Grosso, R Camilli, G Barbabella… - Antimicrobial agents …, 2011 - Am Soc Microbiol
In Streptococcus pyogenes, efflux-mediated erythromycin resistance is associated with the
mef gene, represented mostly by mef (A), although a small portion of strains carry different …

Correlation between genetic features of the mef (A)-msr (D) locus and erythromycin resistance in Streptococcus pyogenes

LA Vitali, MC Di Luca, M Prenna, D Petrelli - Diagnostic Microbiology and …, 2016 - Elsevier
We investigated the correlation between the genetic variation within mef (A)-msr (D)
determinants of efflux-mediated erythromycin resistance in Streptococcus pyogenes and the …