A novel monoclonal antibody has been developed that reacts strongly with human prostatic
cancer, especially tumors of high grade. This antibody (7E11C-5) is currently in Phase 3 …

We have cloned the gene encoding the prostate-specific membrane (PSM) antigen, which is
recognized by the 7E11C-5 antibody. The antigen is strongly expressed in prostate cancer …

Prostate-specific membrane antigen is a type II membrane protein with folate hydrolase
activity produced by prostatic epithelium. The expression of this molecule has also been …

Recently, a novel M r 100,000 prostate-specific membrane glycoprotein (PSM) has been
detected by the prostate-specific monoclonal antibody 7E11-C5, raised against the human …

BACKGROUND Prostate specific membrane antigen (PSMA) is a unique folate hydrolase
that is significantly upregulated in prostate cancer. In a mouse model, PSMA is able to …

Prostate-specific membrane antigen (PSMA) is a potential target in prostate cancer patients
because it is very highly expressed and because it has been reported to be upregulated by …

We have recently cloned a 2.65-kilobase complementary DNA (cDNA) encoding the
prostate-specific membrane antigen (PSM) recognized by the 7E11-C5. 3 anti-prostate …

Prostate specific membrane antigen (PSMA) is a folate glutamyl carboxypeptidase that is
oriented on the plasma membrane of normal and prostate cancer cells. A cytosolic version of …

The expression of the prostate-specific membrane antigen (PSMA) glycoprotein recognized
by the murine monoclonal antibody (MAb) 7E11-C5. 3 has been shown to be highly …

BACKGROUND In an effort to discover new prostate‐specific antigens (PSAs) to enhance
our understanding of the functions and behavior of the prostate and the complex processes …