Expanding the range of ZNF804A variants conferring risk of psychosis

S Steinberg, O Mors, AD Børglum, O Gustafsson… - Molecular …, 2011 - nature.com
A trio of genome-wide association studies recently reported sequence variants at three loci
to be significantly associated with schizophrenia. No sequence polymorphism had been …

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

HJ Williams, N Norton, S Dwyer, V Moskvina… - Molecular …, 2011 - nature.com
A recent genome-wide association study (GWAS) reported evidence for association
between rs1344706 within ZNF804A (encoding zinc-finger protein 804A) and schizophrenia …

Replication of association between schizophrenia and ZNF804A in the Irish case–control study of schizophrenia sample

B Riley, D Thiselton, BS Maher, T Bigdeli… - Molecular …, 2010 - nature.com
A recent genome-wide association study reported association between schizophrenia and
the ZNF804A gene on chromosome 2q32. 1. We attempted to replicate these findings in our …

Allelic differences between Han Chinese and Europeans for functional variants in ZNF804A and their association with schizophrenia

M Li, X Luo, X Xiao, L Shi, X Liu, L Yin… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: ZNF804A is a schizophrenia risk gene that was recently identified by genome-
wide association studies as well as subsequent replications. Although the results are …

The Psychosis Susceptibility Gene ZNF804A: Associations, Functions, and Phenotypes

G Donohoe, DW Morris, A Corvin - Schizophrenia bulletin, 2010 - academic.oup.com
As the first gene to have achieved genome-wide significance for psychosis, ZNF804A has
predictably been a subject of intense research activity. We review the evidence to date for …

Evidence of sex-modulated association of ZNF804A with schizophrenia

F Zhang, Q Chen, T Ye, BK Lipska, RE Straub… - Biological …, 2011 - Elsevier
BACKGROUND: The single nucleotide polymorphism (SNP) rs1344706 in ZNF804A (2q32.
1) has been associated with schizophrenia in a genome-wide association study (GWAS). A …

Identification of loci associated with schizophrenia by genome-wide association and follow-up

MC O'donovan, N Craddock, N Norton, H Williams… - Nature …, 2008 - nature.com
We carried out a genome-wide association study of schizophrenia (479 cases, 2,937
controls) and tested loci with P< 10− 5 in up to 16,726 additional subjects. Of 12 loci …

Population-based and family-based association studies of ZNF804A locus and schizophrenia

R Zhang, SM Lu, C Qiu, XG Liu, CG Gao, TW Guo… - Molecular …, 2011 - nature.com
Thus, ZNF804A is very likely a true susceptibility locus for schizophrenia, albeit one that
confers a small increment in risk. 1, 2 We examined rs1344706 within two independent …

How might ZNF804A variants influence risk for schizophrenia and bipolar disorder? A literature review, synthesis, and bioinformatic analysis

JL Hess, SJ Glatt - American Journal of Medical Genetics Part …, 2014 - Wiley Online Library
The gene that encodes zinc finger protein 804A (ZNF804A) became a candidate risk gene
for schizophrenia (SZ) after surpassing genome‐wide significance thresholds in replicated …

Impact on schizotypal personality trait of a genome-wide supported psychosis variant of the ZNF804A gene

Y Yasuda, R Hashimoto, K Ohi, M Fukumoto… - Neuroscience …, 2011 - Elsevier
Schizophrenia is a complex disorder with a high heritability. Relatives with schizophrenia
have an increased risk not only for schizophrenia but also for schizophrenia spectrum …