cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs
T Fehlmann, S Reinheimer, C Geng, X Su… - Clinical …, 2016 - Springer
Background We present the first sequencing data using the combinatorial probe-anchor
synthesis (cPAS)-based BGISEQ-500 sequencer. Applying cPAS, we investigated the …
synthesis (cPAS)-based BGISEQ-500 sequencer. Applying cPAS, we investigated the …
miRge 2.0 for comprehensive analysis of microRNA sequencing data
Background miRNAs play important roles in the regulation of gene expression. The rapidly
developing field of microRNA sequencing (miRNA-seq; small RNA-seq) needs …
developing field of microRNA sequencing (miRNA-seq; small RNA-seq) needs …
YM500v2: a small RNA sequencing (smRNA-seq) database for human cancer miRNome research
We previously presented YM500, which is an integrated database for miRNA quantification,
isomiR identification, arm switching discovery and novel miRNA prediction from 468 human …
isomiR identification, arm switching discovery and novel miRNA prediction from 468 human …
CAP-miRSeq: a comprehensive analysis pipeline for microRNA sequencing data
Background miRNAs play a key role in normal physiology and various diseases. miRNA
profiling through next generation sequencing (miRNA-seq) has become the main platform …
profiling through next generation sequencing (miRNA-seq) has become the main platform …
QuickMIRSeq: a pipeline for quick and accurate quantification of both known miRNAs and isomiRs by jointly processing multiple samples from microRNA sequencing
Background Genome-wide miRNA expression data can be used to study miRNA
dysregulation comprehensively. Although many open-source tools for microRNA (miRNA) …
dysregulation comprehensively. Although many open-source tools for microRNA (miRNA) …
miRNAs can be generally associated with human pathologies as exemplified for miR-144
Background miRNA profiles are promising biomarker candidates for a manifold of human
pathologies, opening new avenues for diagnosis and prognosis. Beyond studies that …
pathologies, opening new avenues for diagnosis and prognosis. Beyond studies that …
What is normal? Next generation sequencing-driven analysis of the human circulating miRNAOme
DP Tonge, TW Gant - BMC molecular biology, 2016 - Springer
Background MicroRNAs (miRNAs) are short non-protein-coding RNA species that have a
regulatory function in modulating protein translation and degradation of specific mRNAs …
regulatory function in modulating protein translation and degradation of specific mRNAs …
DIANA-miTED: a microRNA tissue expression database
Abstract microRNAs (miRNAs) are short (∼ 23nt) single-stranded non-coding RNAs that act
as potent post-transcriptional gene expression regulators. Information about miRNA …
as potent post-transcriptional gene expression regulators. Information about miRNA …
Evaluation of commercially available small RNASeq library preparation kits using low input RNA
Background Evolving interest in comprehensively profiling the full range of small RNAs
present in small tissue biopsies and in circulating biofluids, and how the profile differs with …
present in small tissue biopsies and in circulating biofluids, and how the profile differs with …
Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs
T Fehlmann, C Backes, M Kahraman… - Nucleic acids …, 2017 - academic.oup.com
The analysis of small RNA NGS data together with the discovery of new small RNAs is
among the foremost challenges in life science. For the analysis of raw high-throughput …
among the foremost challenges in life science. For the analysis of raw high-throughput …