Abstract CD8+ CD25+ cells, which expressed high levels of Foxp3, glucocorticoid-induced
tumor necrosis factor receptor (GITR), CCR8, tumor necrosis factor receptor 2 (TNFR2), and …

A subpopulation of peripheral human CD4+ CD25+ T cells that expresses CD45RO,
histocompatibility leukocyte antigen DR, and intracellular cytotoxic T lymphocyte–associated …

Phenotypic markers, localization, functional activities, and mechanisms of action in vitro of
CD4+ CD25+ T cells, purified from postnatal human thymuses, were investigated. These …

Several types of T regulatory (Treg) cells have been described in both mice and humans,
including natural or professional (CD4+ CD25+ T cells) and adaptive (Th3 and Tr1 cells) …

Summary CD4+ CD25+ regulatory T cells prevent organ‐specific autoimmune diseases in
various animal models. We analysed human lymphoid tissues to identify similar CD25+ …

It has recently been shown that CD4+ CD25+ T cells are immunoregulatory T cells that
prevent CD4+ T-cell–mediated organ-specific autoimmune diseases. In this study, the …

Abstract CD4+ CD25+ T cells are critical mediators of peripheral immune tolerance.
However, many developmental and functional characteristics of these cells are unknown …

Alloantigen specific CD8+ CD28− T suppressor (TS) cells differ from naturally occurring
CD4+ CD25+ T-regulatory (natural TR) cells not only by their phenotype but also by their …

Despite substantial advances in our understanding of CD4+ CD25+ regulatory T cells, a
possible equivalent regulatory subset within the CD8+ T cell population has received less …

T-cell clones generated from both CD4+ CD25+ and CD8+ CD25+ human thymocytes were
assessed for their ability to suppress the proliferative response to allogeneic stimulation of …