Retinoic acid‐induced CD38 expression in HL‐60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels

TJ Lamkin, V Chin, S Varvayanis… - Journal of cellular …, 2006 - Wiley Online Library
Retinoic acid‐induced expression of the CD38 ectoenzyme receptor in HL‐60 human
myeloblastic leukemia cells is regulated by RARα and RXR, and enhanced or prevented cell …

Retinoid-mediated signaling pathways in CD38 antigen expression in myeloid leukemia cells

K Mehta, S Cheema - Leukemia & lymphoma, 1999 - Taylor & Francis
The lymphocyte cell surface antigen CD38, which was originally described as a
differentiation marker, has emerged as an important multifunctional protein. Its most …

Retinoic acid-induced expression of CD38 antigen in myeloid cells is mediated through retinoic acid receptor-α

J Drach, T McQueen, H Engel, M Andreeff… - Cancer research, 1994 - AACR
CD38 is a leukocyte differentiation antigen that has been thought to be a phenotypic marker
of different subpopulations of T-and B-lymphocytes. In myeloid cells, CD38 is expressed …

Involvement of Retinoic Acid Receptor-α–Mediated Signaling Pathway in Induction of CD38 Cell-Surface Antigen

K Mehta, T McQueen, T Manshouri… - Blood, The Journal …, 1997 - ashpublications.org
Human leukocyte antigen CD38, a 45-kD single-chain, transmembrane glycoprotein, is a
bifunctional ectoenzyme that participates in signal transduction pathways involved in the …

Rapid induction of CD38 antigen on myeloid leukemia cells by all trans-retinoic acid

J Drach, SR Zhao, F Malavasi, K Mehta - Biochemical and biophysical …, 1993 - Elsevier
The CD38 or T10 molecule is one of the least understood differentiation antigens. Virtually
no information is available on the regulation and functions of CD38 antigen in hematopoietic …

All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible …

A Uruno, N Noguchi, K Matsuda, K Nata… - Journal of Leukocyte …, 2011 - academic.oup.com
ABSTRACT ATRA and a synthetic RAR agonist tamibarotene (Am80) induce granulocytic
differentiation of human acute leukemia HL-60 cells and have been used in antineoplastic …

Nuclear CD38 in retinoic acid-induced HL-60 cells

L Yalcintepe, I Albeniz, S Adin-Cinar, D Tiryaki… - Experimental cell …, 2005 - Elsevier
The cell surface antigen, CD38, is a 45-kDa transmembrane protein which is predominantly
expressed on hematopoietic cells during differentiation. As a bifunctional ectoenzyme, it …

Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid

Y Alsayed, S Uddin, N Mahmud, F Lekmine… - Journal of Biological …, 2001 - ASBMB
Several signaling pathways are activated by all-trans-retinoic acid (RA) to mediate induction
of differentiation and apoptosis of malignant cells. In the present study we provide evidence …

Retinoid-mediated signaling in CD38 antigen expression

K Mehta - Human CD38 and Related Molecules, 2000 - karger.com
Human CD38 antigen, a 45-kDa type II cell-surface glycoprotein, was initially described by
immunologists as a lymphoid-cell differentiation marker [1]. A subsequent report that the …

Phosphatidylinositol 3‐kinases are involved in the all‐trans retinoic acid‐induced upregulation of CD38 antigen on human haematopoietic cells

D Lewandowski, C Linassier… - British journal of …, 2002 - Wiley Online Library
All‐trans retinoic acid (ATRA) is a specific inducer of CD38 antigen on marrow CD34+ cells
as well as on blast cells in acute promyelocytic and myeloblastic leukaemia. The CD38 …