Progesterone given after traumatic brain injury (TBI) has been shown to reduce the initial
cytotoxic surge of inflammatory factors. We used Western blot techniques to analyze how …

Previous studies suggest that progesterone may possess neuroprotective properties after
traumatic insult but, with the exception of reduced formation of cerebral oedema, limited …

Recent evidence has demonstrated that treatment with progesterone can attenuate many of
the pathophysiological events following traumatic brain injury (TBI) in young adult rats, but …

A single injection of progesterone can attenuate cerebral edema when administered during
the first 24 h after traumatic brain injury (TBI) in rats but this regimen may not always produce …

Background Repeated mild traumatic brain injuries, such as concussions, may result in
cumulative brain damage, neurodegeneration and other chronic neurological impairments …

Following a traumatic brain injury (TBI), the excessive release of interleukin-1β (IL-1β) and
tumor necrosis factor α (TNF-α) is a major cause of cerebral edema, which, in turn, can …

The effects of progesterone on the cellular inflammatory response to frontal cortex injury
were examined on postsurgical days 1, 3, 5, 7 and 9 in male rats treated with progesterone …

Objective: Inflammation is an important component of the response to traumatic brain injury
(TBI). Progesterone has been shown to inhibit neuroinflammation following (TBI) and may …

Previous animal research suggests that progesterone may have powerful neuroprotective
effects in traumatic brain injury (TBI). This experiment tested the hypothesis that …

Although the administration of progesterone has been shown to be neuroprotective in
experimental models of traumatic brain injury (TBI), the mechanisms for this beneficial effect …