Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study

G Matullo, S Guarrera, M Betti, G Fiorito, D Ferrante… - PloS one, 2013 - journals.plos.org
Asbestos exposure is the main risk factor for malignant pleural mesothelioma (MPM), a rare
aggressive tumor. Nevertheless, only 5–17% of those exposed to asbestos develop MPM …

Gene–asbestos interaction in malignant pleural mesothelioma susceptibility

S Tunesi, D Ferrante, D Mirabelli, S Andorno… - …, 2015 - academic.oup.com
Asbestos exposure is the main risk factor for malignant pleural mesothelioma (MPM), a rare
aggressive tumor. Nevertheless, on average less than 10% of subjects highly exposed to …

A genome-wide association study for malignant mesothelioma risk

G Cadby, S Mukherjee, AWB Musk, A Reid, M Garlepp… - Lung Cancer, 2013 - Elsevier
Malignant mesothelioma (MM) is a uniformly fatal tumour of mesothelial cells. MM is caused
by exposure to asbestos however most individuals with documented asbestos exposure do …

[HTML][HTML] Familial risk of pleural mesothelioma increased drastically in certain occupations: a nationwide prospective cohort study

E Kharazmi, T Chen, M Fallah, K Sundquist… - European Journal of …, 2018 - Elsevier
Objective We aimed to explore the effect of occupation on familial risk of pleural
mesothelioma in a nationwide cohort study design. Method The nationwide Swedish Family …

Pleural malignant mesothelioma, genetic susceptibility and asbestos exposure

M Neri, R Filiberti, E Taioli, S Garte, V Paracchini… - Mutation Research …, 2005 - Elsevier
Pleural malignant mesothelioma (MM) is a rare but extremely aggressive cancer. The limited
impact of standard therapeutic treatments on survival rates makes the identification of factors …

[HTML][HTML] The genetic susceptibility in the development of malignant pleural mesothelioma

O Melaiu, F Gemignani, S Landi - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Malignant pleural mesothelioma (MPM) is a cancer of the pleural cavity whose main risk
factor is exposure to asbestos. However, it has been shown that only a minority of exposed …

Matrix metalloproteinases polymorphisms as baseline risk predictors in malignant pleural mesothelioma

D Strbac, K Goricar, V Dolzan, V Kovac - Radiology and oncology, 2018 - sciendo.com
Background. Malignant mesothelioma (MM) is a rare disease, linked to asbestos exposure
in more than 80% of the cases. Matrix metalloproteinases (MMPs) have been identified as …

Risk of malignant pleural mesothelioma and polymorphisms in genes involved in the genome stability and xenobiotics metabolism

F Gemignani, M Neri, F Bottari, R Barale… - Mutation Research …, 2009 - Elsevier
Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer mostly attributable
to asbestos exposure. Many polymorphic genes encoding for xenobiotic and oxidative …

Genetic predisposition for malignant mesothelioma: A concise review

M Betti, A Aspesi, M Sculco, G Matullo… - … Research/Reviews in …, 2019 - Elsevier
Malignant mesothelioma (MM) is an aggressive cancer associated with asbestos exposure.
Studies of familial malignant pleural mesothelioma (MPM) have suggested the existence of …

Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival

L Quetel, C Meiller, JB Assié, Y Blum… - Molecular …, 2020 - Wiley Online Library
Development of precision medicine for malignant pleural mesothelioma (MPM) requires a
deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo …