Novel autoantigens immunogenic in COPD patients

P Leidinger, A Keller, S Heisel, N Ludwig… - Respiratory …, 2009 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a respiratory inflammatory
condition with autoimmune features including IgG autoantibodies. In this study we analyze …

COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype

TA Packard, QZ Li, GP Cosgrove, RP Bowler… - Immunologic …, 2013 - Springer
The role of autoimmune pathology in development and progression of chronic obstructive
pulmonary disease (COPD) is becoming increasingly appreciated. In this study, we …

Identification and clinical association of anti-cytokeratin 18 autoantibody in COPD

YB Kuo, CA Chang, YK Wu, MJ Hsieh, CH Tsai… - Immunology letters, 2010 - Elsevier
The etiology of chronic obstructive pulmonary disease (COPD) remains unclear. A
mechanism involving the autoimmune reaction in the pathogenesis of COPD has been …

Autoantibodies in chronic obstructive pulmonary disease

L Wen, S Krauss-Etschmann, F Petersen… - Frontiers in …, 2018 - frontiersin.org
Chronic obstructive pulmonary disease (COPD), the fourth leading cause of death
worldwide, is characterized by irreversible airflow limitation based on obstructive …

Serum levels of autoantibodies against extracellular antigens and neutrophil granule proteins increase in patients with COPD compared to non-COPD smokers

A Ma, L Wen, J Yin, Y Hu, X Yue, J Li… - … Journal of Chronic …, 2020 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) is a highly prevalent disease
leading to irreversible airflow limitation and is characterized by chronic pulmonary …

Chronic obstructive pulmonary disease: evidence for an autoimmune component

AM Stefanska, PT Walsh - Cellular & molecular immunology, 2009 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterized by an irreversible limitation
on pulmonary airflow associated with chronic inflammation and mucous hypersecretion …

Autoimmunity and COPD: clinical implications

G Caramori, P Ruggeri, A Di Stefano, S Mumby… - Chest, 2018 - Elsevier
COPD is a leading cause of morbidity and mortality worldwide. Long-term cigarette smoking
is the cause of> 90% of COPD cases in Westernized countries. However, only a fraction of …

Autoantibodies in chronic obstructive pulmonary disease: a systematic review

R Byrne, I Todd, PJ Tighe, LC Fairclough - Immunology Letters, 2019 - Elsevier
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a major cause of death
worldwide in which the involvement of autoimmunity has been widely investigated and …

Correlation of severity of chronic obstructive pulmonary disease with potential biomarkers

S Singh, SK Verma, S Kumar, MK Ahmad, A Nischal… - Immunology letters, 2018 - Elsevier
Background Chronic obstructive pulmonary disease (COPD) is a non-specific inflammation,
which involves the airways, lung parenchyma and pulmonary vessels. The inflammation …

Role of autoimmunity in the pathogenesis of chronic obstructive pulmonary disease and pulmonary emphysema

F Nucera, PM Hansbro, KR Paudel, V Casolaro… - Translational …, 2022 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality. Cigarette
smoke is the cause of COPD. However, only a fraction of current and/or former smokers …