Hepatoprotective effects of natural drugs: Current trends, scope, relevance and future perspectives

S Datta, D Aggarwal, N Sehrawat, M Yadav, V Sharma… - Phytomedicine, 2023 - Elsevier
Background: The liver is a well-known player in the metabolism and removal of drugs. Drug
metabolizing enzymes in the liver detoxify drugs and xenobiotics, ultimately leading to the …

The potential effect of phytochemicals and herbal plant remedies for treating drug-induced hepatotoxicity: a review

M Parthasarathy, S Evan Prince - Molecular Biology Reports, 2021 - Springer
Drug-induced liver injury significantly caused by synthetic drugs, and other xenobiotics
contribute to clinical hepatic dysfunction, which has been a substantial challenge for both …

A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives

R Domitrović, I Potočnjak - Archives of toxicology, 2016 - Springer
Hepatoprotective effects of natural compounds have been frequently attributed to their
antioxidant properties and the ability to mobilize endogenous antioxidant defense system …

[PDF][PDF] Hepatotoxicity: Its mechanisms, experimental evaluation and protective strategies

K Gulati, MR Reshi, N Rai, A Ray - Am J Pharmacol. 2018; 1 (1), 2018 - researchgate.net
The liver is a crucial organ for maintenance of gastrointestinal homeostasis and body
function in general. In addition to its role in the digestive process, it also serves as a source …

Herbal Induced Hepatoprotection and Hepatotoxicity: A Critical Review.

O Bedi, KRV Bijjem, P Kumar… - Indian journal of …, 2016 - europepmc.org
Traditional herbal drugs are wonderful remedies for the treatment of various devastating
disorders. Recently, there has been a change in a universal fashion from synthetic to herbal …

Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects

D Singh, MA Khan, HR Siddique - Phytotherapy Research, 2024 - Wiley Online Library
Drug‐induced liver injury (DILI) refers to adverse reactions to small chemical compounds,
biological agents, and medical products. These reactions can manifest as acute or chronic …

[HTML][HTML] Drug-induced liver toxicity and prevention by herbal antioxidants: an overview

D Singh, WC Cho, G Upadhyay - Frontiers in physiology, 2016 - frontiersin.org
The liver is the center for drug and xenobiotic metabolism, which is influenced most with
medication/xenobiotic-mediated toxic activity. Drug-induced hepatotoxicity is common and …

An overview on hepatoprotective activity of natural products

SM Zachariah, N Aleykutty, V Viswanad… - Research Journal of …, 2012 - indianjournals.com
Medicinal practioners have prescribed Ayurveda and drugs from herbal origin as a system of
medicine in India over centuries. Many of the modern drug mainly based on synthetic …

Drug-induced liver injury and anti-hepatotoxic effect of herbal compounds: a metabolic mechanism perspective

J Rani, SB Dhull, PK Rose, MK Kidwai - Phytomedicine, 2024 - Elsevier
Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …

[PDF][PDF] Mechanisms involved in hepatoprotection of different herbal products: a review

A Kumar, N Rai, N Kumar, P Gautam… - Int J Res Pharm …, 2013 - researchgate.net
Since ancient time, herbal products are being used for health remedies. These plant
products are in continuous demand and have an edge over other products in the area of …