Altered coagulation and inflammation contribute to the pathogenesis of ischemic renal
injury. Thrombomodulin is a necessary factor in the anticoagulant protein C pathway and …

Background. Thrombomodulin (TM) is an endothelial anti-coagulant cofactor which also has
anti-inflammatory properties. The present study was performed to investigate the effects of …

Background The thrombomodulin-dependent protein C anticoagulant pathway plays a major
physiologic role in the down-regulation of the coagulation process. In cell culture …

Effects of human soluble thrombomodulin on experimental glomerulonephritis. Background
Coagulation and inflammation are both important processes that contribute to glomerular …

Background Thrombomodulin (TM) is an endothelial cell (EC) membrane-bound
anticoagulant protein that has novel direct cellular effects. TM is shed from EC and becomes …

Thrombomodulin (TM), which is predominantly expressed on the endothelium, plays an
important role in maintaining vascular homeostasis by regulating the coagulation system …

Thrombomodulin (TM) is a thrombin receptor on endothelial cells that is involved in
promoting activation of the anticoagulant protein C pathway during blood coagulation. TM …

Objective—We have recently reported that recombinant human soluble thrombomodulin
(rTM) counteracted capillary leakage associated with engraftment, as well as sinusoidal …

Thrombomodulin (TM) is an endothelial anticoagulant cofactor that promotes thrombin‐
mediated activation of protein C. Recently, we conducted a multicentre, double‐blind …

Background Thrombomodulin (TM), a glycoprotein expressed on the surface of endothelial
cells, transforms protein C into a potent anticoagulant by binding thrombin. TM may be an …