Redundant and regulatory roles for Toll-like receptors in Leishmania infection

P Chauhan, D Shukla… - Clinical & …, 2017 - academic.oup.com
Toll-like receptors (TLRs) are germline-encoded, non-clonal innate immune receptors,
which are often the first receptors to recognize the molecular patterns on pathogens …

[HTML][HTML] Toll-like receptor signaling: a perspective to develop vaccine against leishmaniasis

RK Singh, A Srivastava, N Singh - Microbiological research, 2012 - Elsevier
The toll-like receptors (TLRs) are the sentinel factor of the innate immunity, which are
essential for host defense. These receptors detect the presence of conserved molecular …

Leishmania species‐dependent functional duality of toll‐like receptor 2

A Jafarzadeh, M Nemati, I Sharifi, A Nair, D Shukla… - IUBMB …, 2019 - Wiley Online Library
Toll‐like receptors (TLRs) are a subset of pattern recognition receptors (PRR) in innate
immunity and act as a connecting link between innate and adaptive immune systems …

Toll‐Like Receptors in Leishmania Infections: Guardians or Promoters?

MS Faria, FCG Reis, APCA Lima - Journal of parasitology …, 2012 - Wiley Online Library
Protozoa of the genus Leishmania cause a wide variety of pathologies ranging from self‐
healing skin lesions to visceral damage, depending on the parasite species. The outcome of …

Interdependencies between Toll‐like receptors in Leishmania infection

D Shukla, A Patidar, U Sarma, P Chauhan… - …, 2021 - Wiley Online Library
Multiple pathogen‐associated molecular patterns (PAMPs) on a pathogen's surface imply
their simultaneous recognition by the host cell membrane‐located multiple PAMP‐specific …

Toll-like receptors and leishmaniasis

FF Tuon, VS Amato, HA Bacha, T AlMusawi… - Infection and …, 2008 - Am Soc Microbiol
More than 10 million people around the world are currently affected by Leishmania sp.(33).
Infection with this protozoan parasite continues to be a problem in underdeveloped …

Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis

C Gallego, D Golenbock, MA Gomez… - Infection and …, 2011 - Am Soc Microbiol
Toll-like receptors (TLRs) play a central role in macrophage activation and control of
parasitic infections. Their contribution to the outcome of Leishmania infection is just …

Paradoxical immune response in leishmaniasis: The role of toll‐like receptors in disease progression

IE Bamigbola, S Ali - Parasite immunology, 2022 - Wiley Online Library
Abstract Toll‐like receptors (TLRs), members of pattern recognition receptors, are expressed
on many cells of the innate immune system, and their engagements with antigens regulate …

Enhanced expression of Toll‐like receptors 2 and 4, but not 9, in spleen tissue from patients with visceral leishmaniasis

R Kumar, OP Singh, S Gautam, S Nylen… - Parasite …, 2014 - Wiley Online Library
Toll‐like receptor (TLR) signalling is involved in first‐line defence against L eishmania
parasites by triggering NF‐κB activation and downstream production of proinflammatory …

Toll-Like Receptor 4 Contributes to Efficient Control of Infection with the Protozoan Parasite Leishmania major

P Kropf, MA Freudenberg, M Modolell… - Infection and …, 2004 - Am Soc Microbiol
The essential role of Toll-like receptors (TLR) in innate immune responses to bacterial
pathogens is increasingly recognized, but very little is known about the role of TLRs in host …