Serial procalcitonin predicts mortality in severe sepsis patients: results from the multicenter procalcitonin MOnitoring SEpsis (MOSES) study

P Schuetz, R Birkhahn, R Sherwin, AE Jones… - Critical care …, 2017 - journals.lww.com
Objectives: To prospectively validate that the inability to decrease procalcitonin levels by
more than 80% between baseline and day 4 is associated with increased 28-day all-cause …

The use of procalcitonin in the determination of severity of sepsis, patient outcomes and infection characteristics

I Yunus, A Fasih, Y Wang - PloS one, 2018 - journals.plos.org
Objective The primary objective of this study was to determine the correlation between
procalcitonin values and illness severity by evaluating the degree of end organ dysfunction …

Procalcitonin decrease over 72 hours in US critical care units predicts fatal outcome in sepsis patients

P Schuetz, P Maurer, V Punjabi, A Desai, DN Amin… - Critical Care, 2013 - Springer
Introduction Close monitoring and repeated risk assessment of sepsis patients in the
intensive care unit (ICU) is important for decisions regarding care intensification or early …

Procalcitonin as an early indicator of outcome in sepsis: a prospective observational study

EJ Giamarellos-Bourboulis, I Tsangaris, T Kanni… - Journal of Hospital …, 2011 - Elsevier
This study explores the role of procalcitonin (PCT) in predicting the outcome of sepsis. In a
prospective multicentre observational investigation, blood was sampled within 24h of onset …

Effect of procalcitonin testing on health-care utilization and costs in critically ill patients in the United States

RA Balk, SS Kadri, Z Cao, SB Robinson, C Lipkin… - Chest, 2017 - Elsevier
Background There is a growing use of procalcitonin (PCT) to facilitate the diagnosis and
management of severe sepsis. We investigated the impact of one to two PCT determinations …

Procalcitonin as a prognostic marker for sepsis: a prospective observational study

S Jain, S Sinha, SK Sharma, JC Samantaray… - BMC research …, 2014 - Springer
Background Procalcitonin is useful for the diagnosis of sepsis but its prognostic value
regarding mortality is unclear. This prospective observational study was designed to study …

Procalcitonin levels in survivors and nonsurvivors of sepsis: systematic review and meta-analysis

S Arora, P Singh, PM Singh, A Trikha - Shock, 2015 - journals.lww.com
Procalcitonin (PCT) is an acute-phase reactant that has been used to diagnose and
potentially track the treatment of sepsis. Procalcitonin values rise initially as the infection sets …

Procalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial

Y Shehabi, M Sterba, PM Garrett… - American journal of …, 2014 - atsjournals.org
Rationale: The role of procalcitonin (PCT), a widely used sepsis biomarker, in critically ill
patients with sepsis is undetermined. Objectives: To investigate the effect of a low PCT cut …

Early changes of procalcitonin may advise about prognosis and appropriateness of antimicrobial therapy in sepsis

AP Georgopoulou, A Savva… - Journal of critical …, 2011 - Elsevier
PURPOSE: The objective of this study is to define if early changes of procalcitonin (PCT)
may inform about prognosis and appropriateness of administered therapy in sepsis …

Diagnostic and prognostic value of procalcitonin in patients with septic shock

C Clec'h, F Ferriere, P Karoubi, JP Fosse… - Critical care …, 2004 - journals.lww.com
Objective: To determine whether procalcitonin is a reliable diagnostic and prognostic marker
in septic shock compared with nonseptic shock. Design: Prospective controlled trial. Setting …