Use of antibiotics during pregnancy increases the risk of asthma in early childhood

LG Stensballe, J Simonsen, SM Jensen… - The Journal of …, 2013 - Elsevier
OBJECTIVES: To investigate the hypothesis that mother's use of antibiotics in pregnancy
could influence asthma and eczema in early life. STUDY DESIGN: Subjects were included …

Prenatal and post‐natal exposure to antibiotics and risk of asthma in childhood

J Metsälä, A Lundqvist, LJ Virta, M Kaila… - Clinical & …, 2015 - Wiley Online Library
Background Evidence on the association between post‐natal exposure to antibiotics and the
development of asthma is extensive, but inconsistent and even less is known about prenatal …

Prenatal antibiotic exposure and childhood asthma: a population-based study

K Loewen, B Monchka, SM Mahmud… - European Respiratory …, 2018 - Eur Respiratory Soc
Antibiotic use during infancy alters gut microbiota and immune development and is
associated with an increased risk of childhood asthma. The impact of prenatal antibiotic …

Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study

J Stokholm, A Sevelsted, K Bønnelykke… - The Lancet Respiratory …, 2014 - thelancet.com
Background Maternal use of antibiotics during pregnancy has been associated with the
development of asthmatic disorders in the offspring. The human microbiome has been …

Relationship between prenatal antibiotic use and asthma in at-risk children

B Lapin, J Piorkowski, D Ownby, S Freels… - Annals of Allergy …, 2015 - Elsevier
Background Asthma prevalence has doubled in developed countries during the past 30
years. Pre-and perinatal events are essential in shaping the development of the immune …

Antibiotic use during pregnancy and asthma in preschool children: the influence of confounding

B Mulder, KB Pouwels… - Clinical & …, 2016 - Wiley Online Library
Background A recent study suggested that early‐life intestinal microbiota may play an
important role in the development of childhood asthma, indicating that antibiotics taken …

Prenatal or early-life exposure to antibiotics and risk of childhood asthma: a systematic review

W Murk, KR Risnes, MB Bracken - Pediatrics, 2011 - publications.aap.org
CONTEXT: The increasing prevalence of childhood asthma has been associated with low
microbial exposure as described by the hygiene hypothesis. OBJECTIVE: We sought to …

[PDF][PDF] Antibiotics in fetal and early life and subsequent childhood asthma: nationwide population based study with sibling analysis

AK Örtqvist, C Lundholm, H Kieler, JF Ludvigsson… - Bmj, 2014 - bmj.com
Objective To investigate the association between exposure to antibiotics in fetal and early
life and asthma in childhood, with adjustment for confounding factors. Design Nationwide …

The association of early life exposure to antibiotics and the development of asthma, eczema and atopy in a birth cohort: confounding or causality?

K Wickens, T Ingham, M Epton… - Clinical & …, 2008 - Wiley Online Library
Background In general, studies reporting positive associations between antibiotic exposure
and respiratory and allergic disease have been unable to determine the nature of this …

Relative importance and additive effects of maternal and infant risk factors on childhood asthma

P Wu, AS Feldman, C Rosas-Salazar, K James… - PloS one, 2016 - journals.plos.org
Background Environmental exposures that occur in utero and during early life may
contribute to the development of childhood asthma through alteration of the human …