Prevalence and analysis of CRISPR/Cas systems in Pseudomonas aeruginosa isolates from Greece

LA Gagaletsios, CC Papagiannitsis… - Molecular Genetics and …, 2022 - Springer
The objective of this study was to investigate the prevalence of CRISPR/Cas systems in P.
aeruginosa, isolated from a Greek hospital. Additionally, we aimed to determine the origin of …

Phylogenetic distribution of CRISPR-Cas systems in antibiotic-resistant Pseudomonas aeruginosa

A van Belkum, LB Soriaga, MC LaFave, S Akella… - MBio, 2015 - Am Soc Microbiol
Pseudomonas aeruginosa is an antibiotic-refractory pathogen with a large genome and
extensive genotypic diversity. Historically, P. aeruginosa has been a major model system for …

Genetic characteristics and phylogenetic analysis of Brazilian clinical strains of Pseudomonas aeruginosa harboring CRISPR/Cas systems

AC de Oliveira Luz, WJ da Silva Junior… - Current Genetics, 2021 - Springer
The CRISPR–Cas are adaptive immune systems found in archaea and bacteria, responsible
for providing sequence-specific resistance against foreign DNA. Strains of Pseudomonas …

CRISPR Element Patterns vs. Pathoadaptability of Clinical Pseudomonas aeruginosa Isolates from a Medical Center in Moscow, Russia

M Tyumentseva, Y Mikhaylova, A Prelovskaya… - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa is a member of the ESKAPE opportunistic pathogen group, which
includes six species of the most dangerous microbes. This pathogen is characterized by the …

A new group of phage anti-CRISPR genes inhibits the type IE CRISPR-Cas system of Pseudomonas aeruginosa

A Pawluk, J Bondy-Denomy, VHW Cheung… - MBio, 2014 - Am Soc Microbiol
ABSTRACT CRISPR-Cas systems are one of the most widespread phage resistance
mechanisms in prokaryotes. Our lab recently identified the first examples of phage-borne …

Prevalence, conservation and functional analysis of Yersinia and Escherichia CRISPR regions in clinical Pseudomonas aeruginosa isolates

KC Cady, AS White, JH Hammond… - …, 2011 - microbiologyresearch.org
Here, we report the characterization of 122 Pseudomonas aeruginosa clinical isolates from
three distinct geographical locations: Dartmouth Hitchcock Medical Center in New …

Analysis of direct repeats and spacers of CRISPR/Cas systems type IF in Brazilian clinical strains of Pseudomonas aeruginosa

ACO Luz, JMA da Silva, AM Rezende… - Molecular Genetics and …, 2019 - Springer
CRISPR/Cas is an adaptive immune system found in prokaryotes, with the main function of
protecting these cells from invasion and possible death by mobile genetic elements …

Novel PCR detection of CRISPR/Cas systems in Pseudomonas aeruginosa and its correlation with antibiotic resistance

M Soliman, HS Said, M El-Mowafy, R Barwa - Applied Microbiology and …, 2022 - Springer
CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-
associated proteins) systems are considered as acquired immune mechanisms in Gram …

CRISPR-Cas system, antibiotic resistance and virulence in bacteria: through a common lens

S Roy, S Naha, A Rao, S Basu - Progress in Molecular Biology and …, 2021 - Elsevier
CRISPR-Cas system, antibiotic resistance and virulence are different modes of survival for
the bacteria. CRISPR-Cas is an adaptive immune system that can degrade foreign DNA …

Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

KS Makarova, YI Wolf, J Iranzo, SA Shmakov… - Nature Reviews …, 2020 - nature.com
The number and diversity of known CRISPR–Cas systems have substantially increased in
recent years. Here, we provide an updated evolutionary classification of CRISPR–Cas …