The production of cytokines during aging, except interleukin (IL)‐2, has been neglected in
humans. We measured the in vitro production of IL‐6, tumor necrosis factor (TNF)‐α …

It is well known that aging is associated with various alterations in lymphoid cell functions,
particularly with a progressive decline in immune responsiveness to exogenous antigens …

Elderly persons are more susceptible to bacterial and virus infections and neoplasias than
young adults. This is related to an impaired immune response. Lymphocytes of the elderly …

Elderly people are at risk from an increased incidence of infections. Therefore we have
studied the correlation between the production of several immunological parameters such …

Investigators have reported an increase, decrease, or no effect of age on interleukin-6 (IL-6)
production. Differences in experimental conditions and the health status of subjects may …

The aim of the present study was to compare cytokine secretion in healthy young and old
subjects. Peripheral blood mononuclear cells were isolated from 55 healthy volunteers …

Aging is associated with impairment of immune functions. Age-dependent alterations in T-
cells are well known. Although the pivotal role of monocytes in immune regulation by their …

PURPOSE: Aging is accompanied by a progressive increase in pro-inflammatory cytokine
status. However, little is known about the development of age-dependent modifications in …

Objective. To determine the association among aging, inflammation, and cytokine
production by peripheral blood mononuclear cells. Population and Methods. We examined …

In this study, the changes in some of the cellular components of the immune system and the
activity of the cytokine interleukin 2, important for immune activation and lymphocyte …