Huntington's disease (HD) is a genetically heritable disorder, linked with continuing cell loss
and degeneration mostly in the striatum. Currently, cell therapy approaches in HD have …

Introduction Immune dysfunction, promoted by pro‐inflammatory cytokines, plays a pivotal
role in neurodegeneration associated with Huntington's disease. Aims The aim of this study …

Huntington disease (HD) is an inherited disorder hallmarked by progressive deterioration of
specific neurons, followed by movement and cognitive anomalies. Cell therapy approaches …

Stem cell-based therapy has recently offered a promising alternative for the remedy of
neurodegenerative disorders like Huntington's disease (HD). Herein, we investigated the …

To date, no certain cure has been found for patients with degenerative cerebellar disease. In
this trial, we examined the in vivo and in vitro neuroprotective effects of Sertoli cells (SCs) on …

Background Huntington's disease (HD) is a motor and cognitive neurodegenerative disorder
due to prominent loss of striatal medium spiny neurons (MSNs). Cell replacement using …

Inflammation significantly impacts the progression of Huntington's disease (HD) and the
mutant HTT protein determines a pro‐inflammatory activation of microglia. Mesenchymal …

Intrastriatal administration of mesenchymal stem cells (MSCs) has shown beneficial effects
in rodent models of Huntington disease (HD). However, the invasive nature of surgical …

Epilepsy significantly reduces the patient's quality of life, and we still need to develop new
therapeutic approaches to control it. Transplantation of cells such as Sertoli cells (SCs) …

Objectives: The purpose of this study was to investigate the ability of bone marrow
mesenchymal stem cells (BMSCs) to survive in the striatum and improve motor function in …