Viral transcription is an essential step of SARS-CoV-2 infection after invasion into the target
cells. Antiviral drugs such as remdesivir, which is used to treat COVID-19 patients, targets …

Viral transcription is an essential step of SARS-CoV-2 infection after invasion into the target
cells. Antiviral drugs such as remdesivir, which is used to treat COVID-19 patients, targets …

Most individuals acutely infected with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) exhibit mild symptoms. However, 10 to 20% of those infected develop long …

The exact mechanism of coronavirus replication and transcription is not fully understood;
however, a hallmark of coronavirus transcription is the generation of negative-sense RNA …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses subgenomic RNA
(sgRNA) to produce viral proteins for replication and immune evasion. We apply long-read …

The replication of SARS-CoV-2 and other coronaviruses depends on transcription of
negative-sense RNA intermediates that serve as the templates for the synthesis of positive …

SARS-CoV-2 replication requires the synthesis of a set of structural proteins expressed
through discontinuous transcription of ten subgenomic mRNAs (sgmRNAs). Here, we have …

The worldwide emergence and spread of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) since 2019 has highlighted the importance of rapid and reliable diagnostic …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions within
just a few months, causing severe respiratory disease and mortality. Assays to monitor …

Diagnosis of the ongoing SARS-CoV-2 pandemic is a priority for all countries across the
globe. Currently, reverse transcription quantitative PCR (RT-qPCR) is the gold standard for …