Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest
animals are the single best source of marine natural products. The present review presents …

Marine sponges are productive sources of bioactive secondary metabolites with over 200
new compounds isolated each year, contributing 23% of approved marine drugs so far. This …

In the last decades researchers of natural products chemistry focused their research in a
wide variety of bioactive compounds from marine species. Marine sponges (Porifera) have …

The discovery of new drugs can no longer rely primarily on terrestrial resources, as they
have been heavily exploited for over a century. During the last few decades marine sources …

Marine sponges are sessile invertebrates that can be found in temperate, polar and tropical
regions. They are known to be major contributors of bioactive compounds, which are …

Sponges (phylum Porifera) are sessile marine filter feeders that have developed efficient
defense mechanisms against foreign attackers such as viruses, bacteria, or eukaryotic …

Marine sponges have been considered as a gold mine during the past 50 years, with
respect to the diversity of their secondary metabolites. The biological effects of new …

The subject of this review is the biodiversity of marine sponges and associated microbes
which have been reported to produce therapeutically important compounds, along with the …

Background: Sponges are rich source of bioactive natural products synthesized by the
symbiotic bacteria belonging to different phyla. Due to a competition for space and nutrients …

A growing body of evidence indicates that marine sponge-derived microbes possess the
potential ability to make prolific natural products with therapeutic effects. This review for the …