Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo

MP Murphy, H Bayir, V Belousov, CJ Chang… - Nature …, 2022 - nature.com
Multiple roles of reactive oxygen species (ROS) and their consequences for health and
disease are emerging throughout biological sciences. This development has led …

Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … reviews Molecular cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

[HTML][HTML] Unraveling the biological roles of reactive oxygen species

MP Murphy, A Holmgren, NG Larsson, B Halliwell… - Cell metabolism, 2011 - cell.com
Reactive oxygen species are not only harmful agents that cause oxidative damage in
pathologies, they also have important roles as regulatory agents in a range of biological …

ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

B D'Autréaux, MB Toledano - Nature reviews Molecular cell biology, 2007 - nature.com
Reactive oxygen species (ROS) have been shown to be toxic but also function as signalling
molecules. This biological paradox underlies mechanisms that are important for the integrity …

Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications

AI Casas, VTV Dao, A Daiber, GJ Maghzal… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Enhanced levels of reactive oxygen species (ROS) have been associated with
different disease states. Most attempts to validate and exploit these associations by chronic …

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

H Sies, DP Jones - Nature reviews Molecular cell biology, 2020 - nature.com
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Signal transduction by reactive oxygen species

T Finkel - Journal of Cell Biology, 2011 - rupress.org
Although historically viewed as purely harmful, recent evidence suggests that reactive
oxygen species (ROS) function as important physiological regulators of intracellular …

Chemistry and biology of reactive oxygen species in signaling or stress responses

BC Dickinson, CJ Chang - Nature chemical biology, 2011 - nature.com
Reactive oxygen species (ROS) are a family of molecules that are continuously generated,
transformed and consumed in all living organisms as a consequence of aerobic life. The …

Reactive oxygen species: a radical role in development?

D Hernández-García, CD Wood… - Free Radical Biology …, 2010 - Elsevier
Reactive oxygen species (ROS), mostly derived from mitochondrial activity, can damage
various macromolecules and consequently cause cell death. This ROS activity has been …

Overview of reactive oxygen species

K Krumova, G Cosa - 2016 - books.rsc.org
The increasing concentration of molecular oxygen (O2) in the atmosphere roughly 2.5 billion
years ago, 1, 2 due to oxygenic photosynthesis by cyanobacteria, allowed for the evolution …