MicroRNAs: a puzzling tool in cancer diagnostics and therapy

B D'ANGELO, E Benedetti, A Cimini… - Anticancer …, 2016 - ar.iiarjournals.org
MicroRNAs (miRNAs) constitute a dominating class of small RNAs that regulate diverse
cellular functions. Due the pivotal role of miRNAs in biological processes, a deregulated …

[HTML][HTML] MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies

T Kim, CM Croce - Experimental & molecular medicine, 2023 - nature.com
As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in
cancer development. Since the discovery of the identity and clinical functions of miRNAs …

MicroRNAs in clinical oncology: at the crossroads between promises and problems

SM Metias, E Lianidou, GM Yousef - Journal of clinical pathology, 2009 - jcp.bmj.com
MicroRNAs (miRNAs) are small RNAs that do not code for proteins, but function by
controlling protein expression of other genes. miRNAs have been shown to control cell …

MicroRNAs: novel regulators in the hallmarks of human cancer

K Ruan, X Fang, G Ouyang - Cancer letters, 2009 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs of 18–25 nucleotides in length that
function as negative regulators. miRNAs post-transcriptionally regulate gene expression by …

MicroRNAs as oncogenes and tumor Suppressors

EE Rufino‐Palomares, FJ Reyes‐Zurita… - MicroRNAs in …, 2013 - Wiley Online Library
MicroRNAs (miRNAs) are a recently discovered class of small RNA molecules that regulate
gene expression at the posttranscriptional level. miRNAs maintain the appropriate balance …

MicroRNAs as potential biomarkers in cancer: opportunities and challenges

H Lan, H Lu, X Wang, H Jin - BioMed research international, 2015 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small noncoding RNAs (ncRNAs) that
posttranscriptionally regulate gene expression by targeting their corresponding messenger …

[HTML][HTML] MicroRNAs and cancer: Key paradigms in molecular therapy

W Tan, B Liu, S Qu, G Liang, W Luo… - Oncology …, 2018 - spandidos-publications.com
MicroRNAs (miRNAs) are a type of small non-coding RNA molecule that performs an
important role in post‑transcriptional gene regulation. Since miRNAs were first identified in …

Versatile applications of microRNA in anti-cancer drug discovery: from therapeutics to biomarkers

H Iguchi, N Kosaka, T Ochiya - Current drug discovery …, 2010 - ingentaconnect.com
Over the past several years, microRNAs (miRNAs) have been identified as a fine-tuner in a
wide array of biological processes, including development, cell growth and metabolism …

Potential applications of microRNAs in cancer diagnosis, prognosis, and treatment

S Sandhu, R Garzon - Seminars in oncology, 2011 - Elsevier
Early studies have established that microRNAs (miRNAs) are widely deregulated in cancer
and play a critical role in cancer pathogenesis. Recent research efforts are directed now …

Micro-RNAs: The new potential biomarkers in cancer diagnosis, prognosis and cancer therapy

B Mansoori, A Mohammadi, S Shirjang… - Cellular and Molecular …, 2015 - cellmolbiol.org
MicroRNAs (miRNAs) are a large class of small noncoding RNAs approximately 22
nucleotides in length. They are the main regulators of gene expression, regulating specific …