Multimodal neural correlates of childhood psychopathology

V Kebets, C Piguet, J Chen, LQR Ooi, M Kirschner… - bioRxiv, 2023 - biorxiv.org
Complex structural and functional changes occurring in typical and atypical development
necessitate multidimensional approaches to better understand the risk of developing …

Connectomic alterations linked to transdiagnostic risk for psychopathology at the transition to adolescence

C Sripada, M Angstadt, S Rutherford, A Taxali… - BioRxiv, 2020 - biorxiv.org
BACKGROUND Convergent research identifies a general factor (“P factor”) that confers
transdiagnostic risk for psychopathology. However, brain functional connectivity patterns that …

Unraveling Multimodal Brain Signatures: Deciphering Transdiagnostic Dimensions of Psychopathology in Adolescents

J Xia, N Chen, A Qiu - Advanced Intelligent Systems, 2024 - Wiley Online Library
Adolescent psychiatric disorders arise from intricate interactions of clinical histories and
disruptions in brain development. While connections between psychopathology and brain …

Altered neurocognitive functional connectivity and activation patterns underlie psychopathology in preadolescence

B Lees, LM Squeglia, LM McTeague, MK Forbes… - Biological Psychiatry …, 2021 - Elsevier
Background Neurocognitive deficits are common among youth with mental disorders, and
patterns of aberrant brain function generally cross diagnostic boundaries. This study …

[HTML][HTML] Delineating disorder-general and disorder-specific dimensions of psychopathology from functional brain networks in a developmental clinical sample

I Voldsbekk, R Kjelkenes, A Dahl, MC Holm… - Developmental …, 2023 - Elsevier
The interplay between functional brain network maturation and psychopathology during
development remains elusive. To establish the structure of psychopathology and its …

[HTML][HTML] Voxel-wise multivariate analysis of brain-psychosocial associations in adolescents reveals six latent dimensions of cognition and psychopathology

RA Adams, C Zor, A Mihalik, K Tsirlis, M Brudfors… - Biological Psychiatry …, 2024 - Elsevier
Background Adolescence heralds the onset of much psychopathology, which may be
conceptualized as an emergence of altered covariation between symptoms and brain …

Mapping common grey matter volume deviation across child and adolescent psychiatric disorders

T Li, L Wang, JA Camilleri, X Chen, S Li… - Neuroscience & …, 2020 - Elsevier
Childhood and adolescence represent a time notable for the emergence of many psychiatric
disorders, where comorbidity and co-occurrence of symptoms are well-documented …

[HTML][HTML] Manifold learning uncovers nonlinear interactions between the adolescent brain and social environment that predict psychopathology

EL Busch, MI Conley, A Baskin-Sommers - bioRxiv, 2024 - ncbi.nlm.nih.gov
Background Advanced statistical methods to model the interplay between adolescents and
their social environments are essential for understanding how differences in brain function …

Neural signatures of data-driven psychopathology dimensions at the transition to adolescence

A Modabbernia, G Michelini, A Reichenberg… - European …, 2022 - cambridge.org
Background One of the challenges in human neuroscience is to uncover associations
between brain organization and psychopathology in order to better understand the …

Shared and unique brain network features predict cognition, personality and mental health in childhood

J Chen, A Tam, V Kebets, C Orban, LQR Ooi, S Marek… - BioRxiv, 2020 - biorxiv.org
The manner through which individual differences in brain network organization track
population-level behavioral variability is a fundamental question in systems neuroscience …