Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder of
childhood. Although abnormalities in several brain regions and disturbances of the …

BackgroundBackground: Growing evidence from observational studies indicates a high
prevalence of anxiety in asthma. However, prevalence rates of coexisting anxiety symptoms …

To identify candidate causal genes of asthma, we performed a genome-wide association
study (GWAS) in UK Biobank on a broad asthma definition (n= 56,167 asthma cases and …

STAT6 (signal transducer and activator of transcription 6) is a transcription factor that plays a
central role in the pathophysiology of allergic inflammation. We have identified 16 patients …

To the Editor: In individuals with severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection, the severity of illness ranges from asymptomatic to fatal. 1 The Centers for …

Asthma is a heterogeneous, complex syndrome, and identifying asthma endotypes has
been challenging. We hypothesize that distinct endotypes of asthma arise in disparate …

Bronchiolitis is the most common lower respiratory infection in infants, yet its pathobiology
remains unclear. Here we present blood DNA methylation data from 625 infants hospitalized …

Background Longitudinal trajectories of asthma and allergies from childhood to adulthood
might be differentially associated with lung function and chronic obstructive pulmonary …

Importance Certain psychiatric and immune-related disorders are reciprocal risk factors.
However, the nature of these associations is unclear. Objective To characterize the …

Clinicians handle a growing amount of clinical, biometric, and biomarker data. In this “big
data” era, there is an emerging faith that the answer to all clinical and scientific questions …