The present review examines the pig as a model for physiological studies in human subjects
related to nutrient sensing, appetite regulation, gut barrier function, intestinal microbiota and …

Bitter taste receptors (TAS2Rs or T2Rs) belong to the superfamily of seven-transmembrane
G protein–coupled receptors, which are the targets of> 50% of drugs currently on the market …

Bitter taste perception plays vital roles in animal behavior and fitness. By signaling the
presence of toxins in foods, particularly noxious defense compounds found in plants, it …

The human genome contains∼ 29 bitter taste receptors (T2Rs), which are responsible for
detecting thousands of bitter ligands, including toxic and aversive compounds. This sentinel …

Genome-wide studies of African populations have the potential to reveal powerful insights
into the evolution of our species, as these diverse populations have been exposed to …

The ability to taste bitterness evolved to safeguard most animals, including humans, against
potentially toxic substances, thereby leading to food rejection. Nonetheless, bitter perception …

Research on bitter taste receptors has made enormous progress during recent years.
Although in the early period after the discovery of this highly interesting receptor family …

Among major cereals domesticated as staple food, only sorghum has a high proportion of
cultivars with condensed tannins in grain, which can trigger bitter taste perception in animals …

Twenty years ago, Dominy and colleagues published “The sensory ecology of primate food
perception,” an impactful review that brought new perspectives to understanding primate …

Chemosensation (olfaction, taste) is essential for detecting and assessing foods, such that
dietary shifts elicit evolutionary changes in vertebrate chemosensory genes. The transition …