Supported by a usage history that predates written records and the perception that “natural”
ensures safety, herbal products have increasingly been incorporated into Western health …

The use of herbal/botanical products, also referred to as complementary and alternative
medicines (CAM), worldwide enjoys increasing popularity. It appears in particular highly …

In Part 2 of this review, a critical examination of the pertinent scientific literature is
undertaken in order to assess the interaction risk that popular dietary supplements may pose …

In recent years, the issue of herbal medicine-drug interactions has generated significant
concern. Such interactions can increase the risk for an individual patient, especially with …

Silymarin is an extract from the seeds (fruits) of Silybum marianum that contains
flavonolignans and flavonoids. Although it is frequently used as a hepatoprotective agent, its …

Silymarin, the extract of milk thistle, and its major active flavonolignan silybin, are common
products widely used in the phytotherapy of liver diseases. They also have promising effects …

The therapeutic efficacy of a drug or its unexpected unwanted side effects may depend on
the concurrent use of a medicinal plant. In particular, constituents in the medicinal plant …

Herbal medicines have been widely used for thousands of years, and now are gaining
continued popularity worldwide as a complementary or alternative treatment for a variety of …

Silymarin has long been used as a hepatoprotective remedy. Chronic toxicity studies in
rodents have confirmed that silymarin has a very low toxicity. These data support its history …

There is a continued predisposition of concurrent use of drugs and botanical products. A
general lack of knowledge of the interaction potential together with an under-reporting of …