Bipolar disorder (BD) is the sixth leading cause of disability in the world according to the
World Health Organization and affects nearly six million (∼ 2.5% of the population) adults in …

Personalized medicine (personalized psychiatry in a specific setting) is a new model
towards individualized care, in which knowledge from genomics and other omic pillars …

Lithium is the most effective and well established treatment for bipolar disorder, and it has a
broad array of effects within cellular pathways. However, the specific processes through …

Objective: To compare the efficacy and tolerability of lithium versus quetiapine for the
treatment of manic or mixed episodes in youths with early course bipolar I disorder …

Introduction Bipolar disorder (BD) is a severe and recurrent psychiatric disorder. The
severity of prognosis in BD is mainly linked to the high rate of suicide in this population …

Bipolar disorder (BD) is a psychiatric disease that causes mood swings between manic and
depressed states. Although genetic linkage studies have shown an association between BD …

Bipolar disorder (BD) is a common and disabling psychiatric condition with a severe
socioeconomic impact. BD is treated with mood stabilizers, among which lithium represents …

Lithium is one of the most effect mood-stabilizing drugs prescribed especially for bipolar
disorder. Lithium has wide range effects on different molecular factors and neural …

GSK3B, BDNF, NGF, NRG1, HTR2C, and PIP4K2A play important roles in molecular
mechanisms of psychiatric disorders. GSK3B occupies a central position in these molecular …

Wnt signaling is required for neurogenesis, the fate of neural progenitors, the formation of
neuronal circuits during development, neuron positioning and polarization, axon and …