Phytochemicals have attracted attention in the oncological field because they are
biologically friendly and have relevant pharmacological activities. Thanks to the intense and …

In Part 2 of this review, a critical examination of the pertinent scientific literature is
undertaken in order to assess the interaction risk that popular dietary supplements may pose …

Phytochemicals have been components of man's diet for millennia and are believed to have
played a significant role in steering the functional development of xenobiotic metabolizing …

More than half of Thai patients with cancer take herbal preparations while receiving
anticancer therapy. There is no systematic or scoping review on interactions between …

Herbs, food and dietary supplements (HFDS), can interact significantly with anticancer drug
treatments via cytochrome p450 isoforms (CYP) CYP3A4, CYP2D6, CYP1A2, and CYP2C8 …

Endoplasmic reticulum (ER) stress is involved in neurodegenerative diseases including
Alzheimer's disease (AD), in which dysregulation of double-stranded RNA-dependent …

Understanding the influence of ethnicity on drug exposure is key to patient safety and could
minimize repetitive clinical studies. This analysis aimed to evaluate the ability of …

Metabolites can have pharmacological or toxicological effects, inhibit metabolic enzymes,
and be used as probes of drug-drug interactions or specific cytochrome P450 (P450) …

Physiologically based pharmacokinetic (PBPK) modeling has a number of applications,
including assessing drug–drug interactions (DDIs) in polymorphic populations, and should …

Allicin, one of the major components of garlic, has wide-ranging health properties. However,
the effects of allicin on migration and invasion of breast cancer cells remain unknown. Allicin …