For more than a quarter of a century, macrophage migration inhibitory factor (MIF) has been
a mysterious cytokine. In recent years, MIF has assumed an important role as a pivotal …

Macrophage migration inhibitory (MIF) factor is an immunoregulatory cytokine whose effect
on arresting random immune cell movement was recognized several decades ago. Despite …

The cytokine macrophage migration inhibitory factor (MIF) occupies a unique position in
physiology by its ability to directly regulate the immunosuppressive actions of …

AV411 (ibudilast; 3-isobutyryl-2-isopropylpyrazolo-[1, 5-a] pyridine) is an antiinflammatory
drug that was initially developed for the treatment of bronchial asthma but which also has …

D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the
macrophage migration inhibitory factor (MIF) protein superfamily. MIF is a broadly expressed …

Highlights•MIF acts cytokine, enzyme, endocrine hormone and chaperon-like molecule.•D-
DT, a member of the MIF family, exerts non-redundant effects from MIF.•MIF and D-DT are up …

Acute pancreatitis in its severe form is complicated by multiple organ system dysfunction,
most importantly by pulmonary complications which include hypoxia, acute respiratory …

Background & Aims: Macrophage migration inhibitory factor (MIF), originally described as an
inhibitor of the random migration of macrophages, has been shown recently to be involved …

Macrophage migration inhibitory factor (MIF) is a pleiotropic proinflammatory cytokine that
has been implicated as playing a causative role in many disease states, including sepsis …

Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that has been
associated with many diseases. Most studies found in literature describe MIF as a …