[HTML][HTML] How to improve photodynamic therapy-induced antitumor immunity for cancer treatment?

M Zhang, Y Zhao, H Ma, Y Sun, J Cao - Theranostics, 2022 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a promising method of tumor ablation and function-
preserving oncological intervention, which is minimally invasive, repeatable, and has …

Self‐Sacrificially Degradable Pseudo‐Semiconducting Polymer Nanoparticles that Integrate NIR‐II Fluorescence Bioimaging, Photodynamic Immunotherapy, and …

D Tang, Y Yu, J Zhang, X Dong, C Liu… - Advanced …, 2022 - Wiley Online Library
Semiconducting polymers (SP) hold great promise for cancer phototherapy due to their
excellent optical properties; however, their clinical application is still hampered by their poor …

Immuno-photodynamic Therapy (IPDT): Organic Photosensitizers and Their Application in Cancer Ablation

Y Lu, W Sun, J Du, J Fan, X Peng - JACS Au, 2023 - ACS Publications
Photosensitizer-based photodynamic therapy (PDT) has been considered as a promising
modality for fighting diverse types of cancers. PDT directly inhibits local tumors by a …

Evoking tumor associated macrophages by mitochondria-targeted magnetothermal immunogenic cell death for cancer immunotherapy

H Jiang, H Fu, Y Guo, P Hu, J Shi - Biomaterials, 2022 - Elsevier
Immunogenic cell death (ICD) based on endoplasmic reticulum (ER) stress has been widely
studied as the fundamentals of cancer immunotherapy. However, the currently available ICD …

Dithiol‐Activated Bioorthogonal Chemistry for Endoplasmic Reticulum‐Targeted Synergistic Chemophototherapy

J Sun, X Zhang, X Wang, J Peng… - Angewandte Chemie …, 2022 - Wiley Online Library
The controlled intracellular release of nitrite is still an unmet challenge due to the lack of bio‐
friendly donors, and the antitumor effect of nitrite is limited by its physiologically inert activity …

Precise gliomas therapy: Hypoxia-activated prodrugs sensitized by nano-photosensitizers

H Zhang, C Shi, F Han, M Li, H Ma, R Sui, S Long… - Biomaterials, 2022 - Elsevier
Hypoxia is one of the prominent features of solid tumors. Hypoxia activated prodrugs
(HAPs), selectively killing hypoxic cells, possess the potential to transform hypoxia from a …

Facile Access to Far‐Red Fluorescent Probes with Through‐Space Charge‐Transfer Effects for In Vivo Two‐Photon Microscopy of the Mouse Cerebrovascular System

Y Hong, W Geng, T Zhang, G Gong, C Li… - Angewandte …, 2022 - Wiley Online Library
Much effort has been devoted to the generation of fluorescent probes by synthetic
approaches. In this study, we developed a facile strategy to construct far‐red fluorescent …

In situ observation of lysosomal hypobromous acid fluctuations in the brain of mice with depression phenotypes by two-photon fluorescence imaging

H Zhu, P Jia, X Wang, Y Tian, C Liu, X Li… - Analytical …, 2022 - ACS Publications
Excessive oxidative stress is the main cause of neurotransmitter metabolism disorder in the
brain with depression. Lysosomal hypobromic acid (HOBr) is an important reactive oxygen …

A Tumor‐Specific Platform of Peroxynitrite Triggering Ferroptosis of Cancer Cells

D Huang, H Huang, M Li, J Fan, W Sun… - Advanced Functional …, 2022 - Wiley Online Library
Peroxynitrite (ONOO−) is a potent oxidant and nucleophile participating in a variety of
pathophysiological processes as well as playing a major role in cancer therapy. However …

Tumor Cell‐Responsive Photodynamic Immunoagent for Immunogenicity‐Enhanced Orthotopic and Remote Tumor Therapy

Y Chen, T Xiong, X Zhao, J Du, W Sun… - Advanced …, 2023 - Wiley Online Library
Combining photodynamic therapy (PDT) and immune checkpoint blockades is an efficient
method to maximize immunotherapeutic outcome by boosting tumor immunogenicity and …