Hepatocellular carcinoma (HCC) is currently the sixth most common type of cancer with a
high mortality rate and an increasing incidence worldwide. Its etiology is usually linked to …

The discipline of hepatology has advanced rapidly through the efforts of investigators in
many countries. Inevitably, this advance has been accompanied by the creation of a large …

This guidance provides a data-supported approach to the diagnosis, staging, and treatment
of patients diagnosed with hepatocellular carcinoma (HCC). A guidance document is …

Malignant cells often display defects in autophagy, an evolutionarily conserved pathway for
degrading long-lived proteins and cytoplasmic organelles. However, as yet, there is no …

Materials and Methods Twenty-six resected cases of nodules from 23 patients with chronic
hepatitis or cirrhosis caused by hepatitis B or Abbreviations: GPC3, glypican-3; GS …

Reduced nicotinamide adenine dinucleotide, NADH, is a major electron donor in the
oxidative phosphorylation and glycolytic pathways in cells. As a result, there has been …

The blood supply of hepatocellular carcinoma (HCC) is primarily arterial. Recent studies
reported differences of vascular, especially arterial, supply among low-and high-grade …

HCC is not a major killer among malignant diseases in Western countries, and until recently
few Western hepatologists were interested in this cancer. After the demonstration of an …

It has been established that small, equivocal nodular lesions such as dysplastic nodules
(DNs) and small well-differentiated hepatocellular carcinomas (early HCCs) are frequently …

Context.—There is increasing evidence to support a multistep model of the process of
human hepatocarcinogenesis. Precursor lesions are characterized by the appearance of …