Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations

A McCleery, KH Nuechterlein - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
Despite effective pharmacological treatments for psychotic symptoms (eg, hallucinations,
delusions), functional outcomes for people with psychotic disorders are often disappointing …

[HTML][HTML] The relationship between cognition and functioning in schizophrenia: A semi-systematic review

S Kharawala, C Hastedt, J Podhorna, H Shukla… - Schizophrenia Research …, 2022 - Elsevier
In schizophrenia, impairments in neurocognition (NC) and social cognition (SC) are
associated with reduced functional capacity (FC) and poor real-world functioning (RWF). In …

Transfer Learning of Fuzzy Spatio-Temporal Rules in a Brain-Inspired Spiking Neural Network Architecture: A Case Study on Spatio-Temporal Brain Data

NK Kasabov, Y Tan, M Doborjeh, E Tu… - … on Fuzzy Systems, 2023 - ieeexplore.ieee.org
The article demonstrates for the first time that a brain-inspired spiking neural network (SNN)
architecture can be used not only to learn spatio-temporal data, but also to extract fuzzy …

[PDF][PDF] Pleiotropic meta-analysis of cognition, education, and schizophrenia differentiates roles of early neurodevelopmental and adult synaptic pathways

M Lam, WD Hill, JW Trampush, J Yu, E Knowles… - The American Journal of …, 2019 - cell.com
Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both
the phenotypic and the genetic level. Paradoxically, a modest but consistent positive genetic …

[HTML][HTML] Cannabidiol and amisulpride improve cognition in acute schizophrenia in an explorative, double-blind, active-controlled, randomized clinical trial

FM Leweke, C Rohleder, CW Gerth… - Frontiers in …, 2021 - frontiersin.org
Cannabidiol (CBD), a principal phytocannabinoid constituent, has demonstrated
antipsychotic properties in recent clinical trials. While it has also been suggested a …

[HTML][HTML] Subcortical dopamine and cognition in schizophrenia: Looking beyond psychosis in preclinical models

KA Conn, THJ Burne, JP Kesby - Frontiers in Neuroscience, 2020 - frontiersin.org
Schizophrenia is characterized by positive, negative and cognitive symptoms. All current
antipsychotic treatments feature dopamine-receptor antagonism that is relatively effective at …

Cognition, social cognition, and functional capacity in early-onset schizophrenia

PD Harvey, EC Isner - Child and Adolescent Psychiatric …, 2020 - childpsych.theclinics.com
Schizophrenia is well known for its positive and negative symptoms that form the definitional
core of the disorder. However, the cognitive deficits also present have emerged as an area …

[HTML][HTML] A systematic review of premorbid cognitive functioning and its timing of onset in schizophrenia spectrum disorders

CR Mohn-Haugen, C Mohn, F Larøi, CM Teigset… - Schizophrenia Research …, 2022 - Elsevier
Cognitive impairments are core features of established schizophrenia spectrum disorders
(SSD). However, it remains unclear whether specific cognitive functions are differentially …

Meta-analysis of longitudinal neurocognitive performance in people at clinical high-risk for psychosis

EP Hedges, C See, S Si, P McGuire… - Psychological …, 2022 - cambridge.org
Persons at clinical high-risk for psychosis (CHR) are characterised by specific
neurocognitive deficits. However, the course of neurocognitive performance during the …

Association between the duration of untreated psychosis and selective cognitive performance in community-dwelling individuals with chronic untreated schizophrenia …

WS Stone, B Cai, X Liu, MMR Grivel, G Yu, Y Xu… - JAMA …, 2020 - jamanetwork.com
Importance Cognitive deficits constitute core features of schizophrenia, but the trajectories of
cognitive difficulties in chronic untreated schizophrenia remain unclear. Objective To assess …