Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment
RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …
functioning associated with the disorder and are not responsive to existing treatments. In this …
[HTML][HTML] The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design
The ABCD twin study will elucidate the genetic and environmental contributions to a wide
range of mental and physical health outcomes in children, including substance use, brain …
range of mental and physical health outcomes in children, including substance use, brain …
Shared polygenic risk for ADHD, executive dysfunction and other psychiatric disorders
S Chang, L Yang, Y Wang, SV Faraone - Translational Psychiatry, 2020 - nature.com
Many psychiatric disorders are associated with impaired executive functioning (EF). The
associated EF component varies by psychiatric disorders, and this variation might be due to …
associated EF component varies by psychiatric disorders, and this variation might be due to …
[HTML][HTML] The role of childhood trauma in cognitive performance in schizophrenia and bipolar disorder–A systematic review
MR Dauvermann, G Donohoe - Schizophrenia Research: Cognition, 2019 - Elsevier
Childhood trauma (CT) has repeatedly been associated with cognitive deficits in patients
with psychosis but many inconsistencies have been reported so that the nature of the …
with psychosis but many inconsistencies have been reported so that the nature of the …
Assessment of neurocognitive functions in 7-year-old children at familial high risk for schizophrenia or bipolar disorder: the Danish high risk and resilience study VIA 7
Importance Children at familial high risk of schizophrenia spectrum disorders (FHR-SZ) or
bipolar disorder (FHR-BP) exhibit neurocognitive impairments. Large studies of …
bipolar disorder (FHR-BP) exhibit neurocognitive impairments. Large studies of …
[HTML][HTML] Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia
Brain aging, which involves a progressive loss of neuronal functions, has been reported to
be premature accelerated in probands affected by schizophrenia (SCZ). Evidence shows …
be premature accelerated in probands affected by schizophrenia (SCZ). Evidence shows …
Glutamatergic regulation of cognition and functional brain connectivity: insights from pharmacological, genetic and translational schizophrenia research
MR Dauvermann, G Lee… - British journal of …, 2017 - Wiley Online Library
The pharmacological modulation of glutamatergic neurotransmission to improve cognitive
function has been a focus of intensive research, particularly in relation to the cognitive …
function has been a focus of intensive research, particularly in relation to the cognitive …
Baseline cortical thickness reductions in clinical high risk for psychosis: brain regions associated with conversion to psychosis versus non-conversion as assessed at …
Objective To assess cortical thickness (CT) and surface area (SA) of frontal, temporal, and
parietal brain regions in a large clinical high risk for psychosis (CHR) sample, and to identify …
parietal brain regions in a large clinical high risk for psychosis (CHR) sample, and to identify …
Social cognition, language, and social behavior in 7-year-old children at familial high-risk of developing schizophrenia or bipolar disorder: the danish high risk and …
CJ Christiani, JRM Jepsen, A Thorup… - Schizophrenia …, 2019 - academic.oup.com
Objective To characterize social cognition, language, and social behavior as potentially
shared vulnerability markers in children at familial high-risk of schizophrenia (FHR-SZ) and …
shared vulnerability markers in children at familial high-risk of schizophrenia (FHR-SZ) and …
Genetic influence on cognitive development between childhood and adulthood
Successful cognitive development between childhood and adulthood has important
consequences for future mental and physical wellbeing, as well as occupational and …
consequences for future mental and physical wellbeing, as well as occupational and …