Brain insulin signaling as a potential mediator of early life adversity effects on physical and mental health
B Alberry, PP Silveira - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
In numerous brain structures, insulin signaling modulates the homeostatic processes,
sensitivity to reward pathways, executive function, memory, and cognition. Through human …
sensitivity to reward pathways, executive function, memory, and cognition. Through human …
[HTML][HTML] Temporally ordered associations between type 2 diabetes and brain disorders–a Danish register-based cohort study
Background Type 2 diabetes mellitus (T2DM) is linked with several neurodegenerative and
psychiatric disorders, either as a comorbid condition or as a risk factor. We aimed to expand …
psychiatric disorders, either as a comorbid condition or as a risk factor. We aimed to expand …
Incidence and Factors Associated with Hyperglycemia in patients with first hospitalization for Major Depression disorder: a large cross-sectional sample
S Qi, Y Xu, K Zeng, Y Li, J Ma - Neuropsychiatric Disease and …, 2023 - Taylor & Francis
Purpose Major depressive disorder (MDD) is a mood disorder characterized by persistent
spontaneous depression and has a high rate of disability and mortality. There is a complex …
spontaneous depression and has a high rate of disability and mortality. There is a complex …
Associations of polygenic risks, depression, and obesity-related traits in Taiwan Biobank
Background The comorbidity of obesity and major depressive disorder (MDD) may be
attributable to a bidirectional relationship and shared genetic influence. We aimed to …
attributable to a bidirectional relationship and shared genetic influence. We aimed to …
[HTML][HTML] Association of substance use and other psychiatric disorders with all-cause and external-cause mortality in individuals given community sentences in Sweden …
D Yukhnenko, N Blackwood, P Lichtenstein… - The Lancet Regional …, 2023 - thelancet.com
Background Consistently high rates of premature mortality have been reported in individuals
who receive community sentences. However, few studies have explored potential modifiable …
who receive community sentences. However, few studies have explored potential modifiable …
[HTML][HTML] Genetic predisposition and antipsychotic treatment effect on metabolic syndrome in schizophrenia: a ten-year follow-up study using the Estonian Biobank
Background Schizophrenia (SCZ) patients exhibit 30% higher prevalence of metabolic
syndrome (MetS) compared to the general population with its suboptimal management …
syndrome (MetS) compared to the general population with its suboptimal management …
[HTML][HTML] Association of type 2 diabetes with family history of diabetes, diabetes biomarkers, mental and physical disorders in a Kenyan setting
This study aimed to determine the degree of family relations and associated socio-
demographics characteristics, clinical/physical and mental disorders in type 2 diabetes …
demographics characteristics, clinical/physical and mental disorders in type 2 diabetes …
Antipsychotics and the risk of diabetes and death among adults with serious mental illnesses
J Poulos, SLT Normand, K Zelevinsky… - Psychological …, 2023 - cambridge.org
BackgroundIndividuals with schizophrenia exposed to second-generation antipsychotics
(SGA) have an increased risk for diabetes, with aripiprazole purportedly a safer drug. Less is …
(SGA) have an increased risk for diabetes, with aripiprazole purportedly a safer drug. Less is …
Relationship between mood disorders and substance involvement and the shared genetic liabilities: A population-based study in Taiwan
Background This study explored the phenotypic association of mood disorders, including
major depressive disorder (MDD) and bipolar disorder (BPD), with a range of substance …
major depressive disorder (MDD) and bipolar disorder (BPD), with a range of substance …
Independent effect and joint effect of polygenic liabilities for schizophrenia and bipolar disorder on cognitive aging and education attainment
To elucidate the specific and shared genetic background of schizophrenia (SCZ) and bipolar
disorder (BPD) to better understand their nosology, this study explored the independent and …
disorder (BPD) to better understand their nosology, this study explored the independent and …