Promotion of good mental health, prevention, and early intervention before/at the onset of
mental disorders improve outcomes. However, the range and peak ages at onset for mental …

Bipolar disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …

Large-scale genomic investigations have just begun to illuminate the molecular genetic
contributions to major psychiatric illnesses, ranging from small-effect-size common variants …

Defining the environmental context in which genes enhance disease susceptibility can
provide insight into the pathogenesis of complex disorders. We report that the intra-uterine …

The neurodevelopmental model of schizophrenia, which posits that the illness is the end
state of abnormal neurodevelopmental processes that started years before the illness onset …

The genetic bases of neuropsychiatric disorders are beginning to yield to scientific inquiry.
Genome-wide studies of copy number variation (CNV) have given rise to a new …

A small number of rare, recurrent genomic copy number variants (CNVs) are known to
substantially increase susceptibility to schizophrenia. As a consequence of the low fecundity …

OBJECTIVE: The distinct trajectories of patients with autism spectrum disorders (ASDs) have
not been extensively studied, particularly regarding clinical manifestations beyond the …

Objectives Use electronic health records Autism Spectrum Disorder (ASD) to assess the
comorbidity burden of ASD in children and young adults. Study Design A retrospective …

BackgroundA number of copy number variants (CNVs) have been suggested as
susceptibility factors for schizophrenia. For some of these the data remain equivocal, and the …