SPASCER: spatial transcriptomics annotation at single-cell resolution

Z Fan, Y Luo, H Lu, T Wang, YZ Feng… - Nucleic Acids …, 2023 - academic.oup.com
In recent years, the explosive growth of spatial technologies has enabled the
characterization of spatial heterogeneity of tissue architectures. Compared to traditional …

Proximal tubule responses to injury: interrogation by single-cell transcriptomics

PE Cippà, AP McMahon - Current Opinion in Nephrology and …, 2023 - journals.lww.com
We provide an update on single-cell technologies and we summarize the recent discoveries
on the cellular response to injury in proximal tubule cells from the early response in AKI, to …

[HTML][HTML] Spatial transcriptomics in human biomedical research and clinical application

W Hu, Y Zhang, J Mei, X Fang - Current Medicine, 2023 - Springer
Over the past 15 years, single-cell RNA sequencing (scRNA-seq) technology, in
combination with other omics, has revealed the mechanisms of human development …

Conundrums of choice of 'normal'kidney tissue for single cell studies

S Jain - Current Opinion in Nephrology and Hypertension, 2023 - journals.lww.com
Committing to a particular reference or 'normal'tissue has significant implications in
interpretation of data from disease samples or in ageing. Voluntarily donated kidney tissue …

[HTML][HTML] Three-dimensional reconstruction of fetal rhesus macaque kidneys at single-cell resolution reveals complex inter-relation of structures

L Dequiedt, A Forjaz, JO Lo, O McCarty, PH Wu… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Kidneys are among the most structurally complex organs in the body. Their architecture is
critical to ensure proper function and is often impacted by diseases such as diabetes and …