High-depth African genomes inform human migration and health

A Choudhury, S Aron, LR Botigué, D Sengupta… - Nature, 2020 - nature.com
The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …

Evolutionary genetics and admixture in African populations

A Pfennig, LN Petersen, P Kachambwa… - Genome Biology and …, 2023 - academic.oup.com
As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

S Fan, JP Spence, Y Feng, MEB Hansen, J Terhorst… - Cell, 2023 - cell.com
We conduct high coverage (> 30×) whole-genome sequencing of 180 individuals from 12
indigenous African populations. We identify millions of unreported variants, many predicted …

[HTML][HTML] African population history: an ancient DNA perspective

M Vicente, CM Schlebusch - Current Opinion in Genetics & Development, 2020 - Elsevier
The history of human populations in Africa is complex and includes various demographic
events that influenced patterns of genetic variation across the continent. Through genetic …

[PDF][PDF] Uganda genome resource enables insights into population history and genomic discovery in Africa

D Gurdasani, T Carstensen, S Fatumo, G Chen… - Cell, 2019 - cell.com
Genomic studies in African populations provide unique opportunities to understand disease
etiology, human diversity, and population history. In the largest study of its kind, comprising …

Ancient DNA reveals a multistep spread of the first herders into sub-Saharan Africa

ME Prendergast, M Lipson, EA Sawchuk, I Olalde… - Science, 2019 - science.org
INTRODUCTION Cattle, sheep, and goats appeared in eastern Africa 5000 years ago,
catalyzing the spread of herding throughout sub-Saharan Africa. Archaeologists have long …

[HTML][HTML] African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations

S Fan, DE Kelly, MH Beltrame, MEB Hansen, S Mallick… - Genome Biology, 2019 - Springer
Background Africa is the origin of modern humans within the past 300 thousand years. To
infer the complex demographic history of African populations and adaptation to diverse …

[HTML][HTML] Evidence of the interplay of genetics and culture in Ethiopia

S López, A Tarekegn, G Band, L van Dorp… - Nature …, 2021 - nature.com
The rich linguistic, ethnic and cultural diversity of Ethiopia provides an unprecedented
opportunity to understand the level to which cultural factors correlate with–and shape …

[PDF][PDF] Hunter-gatherer genomes reveal diverse demographic trajectories during the rise of farming in Eastern Africa

S Gopalan, REW Berl, JW Myrick, ZH Garfield… - Current Biology, 2022 - cell.com
The fate of hunting and gathering populations following the rise of agriculture and
pastoralism remains a topic of debate in the study of human prehistory. Studies of ancient …

[HTML][HTML] The genetic legacy of the expansion of Bantu-speaking peoples in Africa

CA Fortes-Lima, C Burgarella, R Hammarén… - Nature, 2024 - nature.com
The expansion of people speaking Bantu languages is the most dramatic demographic
event in Late Holocene Africa and fundamentally reshaped the linguistic, cultural and …