African Americans (AAs) have been underrepresented in polygenic risk score (PRS) studies.
Herein, we integrated genome-wide data from multiple observational studies on type 2 …

ABSTRACT Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic and
environmental risk factors that disproportionately afflicts communities of color. Leveraging …

Abstract Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic
and environmental risk factors that disproportionately afflicts communities of color …

Aims/hypothesis There is limited information on how polygenic scores (PSs), based on
variants from genome-wide association studies (GWASs) of type 2 diabetes, add to clinical …

OBJECTIVE Polygenic prediction of type 2 diabetes (T2D) in continental Africans is
adversely affected by the limited number of genome-wide association studies (GWAS) of …

Genomic discovery and characterization of risk loci for type 2 diabetes (T2D) have been
conducted primarily in individuals of European ancestry. We conducted a multiethnic …

With the rise in the prevalence of type 2 diabetes (T2D), as well as undiagnosed cases of
T2D and prediabetes (25% and 90%, respectively), early detection is imperative to minimize …

Polygenic risk scores (PRS) quantify the genetic liability to disease and are calculated using
an individual's genotype profile and disease‐specific genome‐wide association study …

Over the past three decades, the number of people globally with diabetes mellitus has more
than doubled. It is estimated that by 2030, 439 million people will be suffering from the …

Abstract Background Hispanic/Latino (HL) populations bear a disproportionately high
burden of type 2 diabetes (T2D). The ability to predict T2D genetic risk using polygenic risk …