Abnormalities in functional connectivity between brain areas have been postulated as an
important pathophysiological mechanism underlying schizophrenia,. In particular …

Schizophrenia has a heritability of 60-80% 1, much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Schizophrenia has a heritability of 60–80%, much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Inherited alleles account for most of the genetic risk for schizophrenia. However, new (de
novo) mutations, in the form of large chromosomal copy number changes, occur in a small …

Effective treatment for schizophrenia is still an unmet clinical need. Alleviating problems
associated with cognitive impairment and finding the root of the disease remain priorities for …

DOPAMINERGIC dysregulation remains an empirical cornerstone for theories concerning
the causation of schizophrenia. Evidence for a dopamine system dysfunction in …

Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by
hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80%,. We …

Splitting schizophrenia Page 1 © 1988 Nature Publishing Group _N_A_T_ll_R_E_V_(_)l_ ..
_.1_.IC_, _111_N_(_JV_E_.M_B_E_"R_llJ_H_K _ _ _ _ _ _ NEWS AND VIEWS------------------I_OS …

Schizophrenia is a complex disorder, caused by both genetic and environmental factors and
their interactions. Research on pathogenesis has traditionally focused on neurotransmitter …

Schizophrenia is a heritable brain illness with unknown pathogenic mechanisms.
Schizophrenia's strongest genetic association at a population level involves variation in the …