Effective treatment for schizophrenia is still an unmet clinical need. Alleviating problems
associated with cognitive impairment and finding the root of the disease remain priorities for …

Studies of schizophrenia have been plagued by shortcomings such as weak genetic
association with disease, inadequate animal models and limited replication of gene …

Although available medications such as dopamine D2 receptor antagonists relieve
symptoms of acute psychosis, they have substantial side effects and provide limited relief of …

From genetics to physiology at last | Nature Skip to main content Thank you for visiting
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Over 100 genetic loci harbor schizophrenia-associated variants, yet how these variants
confer liability is uncertain. The CommonMind Consortium sequenced RNA from …

Genesis of a complex disease | Nature Skip to main content Thank you for visiting nature.com.
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Schizophrenia genetics complements its mechanistic understanding | Nature Neuroscience
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Schizophrenia is a complex disorder, caused by both genetic and environmental factors and
their interactions. Research on pathogenesis has traditionally focused on neurotransmitter …

Functional and structural brain imaging has identified neural and neurotransmitter systems
involved in schizophrenia and their link to cognitive and behavioural disturbances such as …

Genetic origins of schizophrenia find common ground Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …