Population genetics continues to identify genetic variants associated with diseases of the
immune system and offers a unique opportunity to discover mechanisms of immune …

CARD9 is a caspase recruitment domain-containing signaling protein that plays a critical
role in innate and adaptive immunity. It has been widely demonstrated that CARD9 adaptor …

CARD9 is a signaling adaptor protein that is involved in the transduction of signals from a
variety of innate pattern recognition receptors, including the C-type lectin receptors and …

Caspase recruitment domain protein 9 (CARD9) forms essential signaling complexes in the
innate immune system that integrate cues from C-type lectin receptors and specific …

CARD9 is a central component of anti-fungal innate immune signaling via C-type lectin
receptors, and several immune-related disorders are associated with CARD9 alterations …

Neutrophils are terminally differentiated cells with limited transcriptional activity. The
biological function of their gene expression changes is poorly understood. CARD9 regulates …

Caspase recruitment domain-containing protein (Card) 9 is a nonredundant adapter protein
that functions in the innate immune system in the assembly of multifunctional signaling …

CARD9 is a caspase recruitment domain‐containing signaling protein that is highly
expressed in dendritic cells and in macrophages. Work over the last two years has identified …

CARD11 functions as a key signaling scaffold that controls antigen-induced lymphocyte
activation during the adaptive immune response. Somatic mutations in CARD11 are …

The caspase-recruitment domain–containing adaptor protein CARD9 regulates the innate
signaling responses to fungal infection. Here we show that CARD9 is required for innate …