Importance Most previous genome-wide association studies (GWAS) of depression have
used data from individuals of European descent. This limits the understanding of the …

Despite strong evidence supporting the heritability of major depressive disorder (MDD),
previous genome-wide studies were unable to identify risk loci among individuals of …

Background The genetics of depression has been explored in genome-wide association
studies that focused on either major depressive disorder or depressive symptoms with …

BACKGROUND: Depression is a heritable trait that exists on a continuum of varying severity
and duration. Yet, the search for genetic variants associated with depression has had few …

Abstract Purpose of Review We will describe the success of recent genome-wide
association studies that identify genetic variants associated with depression and outline the …

Depression is the most prevalent mental disorder with substantial morbidity and mortality.
Although genome-wide association studies (GWASs) have identified multiple risk variants …

Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

Importance Genetic studies with broad definitions of depression may not capture genetic risk
specific to major depressive disorder (MDD), raising questions about how depression …

The recent successful genome-wide association studies (GWASs) for depression have
yielded more than 80 replicated loci and brought back the excitement that had evaporated …

Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …