Gene–environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach

V Warrier, ASF Kwong, M Luo, S Dalvie, J Croft… - The Lancet …, 2021 - thelancet.com
Background Childhood maltreatment is associated with poor mental and physical health.
However, the mechanisms of gene–environment correlations and the potential causal …

Genomic influences on self-reported childhood maltreatment

S Dalvie, AX Maihofer, JRI Coleman, B Bradley… - Translational …, 2020 - nature.com
Childhood maltreatment is highly prevalent and serves as a risk factor for mental and
physical disorders. Self-reported childhood maltreatment appears heritable, but the specific …

Sensitive periods in development and risk for psychiatric disorders and related endpoints: a systematic review of child maltreatment findings

JD Schaefer, TW Cheng, EC Dunn - The Lancet Psychiatry, 2022 - thelancet.com
Variation in the mental health of people who have experienced childhood maltreatment is
substantial. One hypothesis is that this variation is attributable, in part, to the timing of …

The burden of mental ill health associated with childhood maltreatment in the UK, using The Health Improvement Network database: a population-based retrospective …

JS Chandan, T Thomas, KM Gokhale… - The Lancet …, 2019 - thelancet.com
Background Childhood maltreatment is a global public health, human rights, and moral
issue that is associated with a substantial mental health burden. We aimed to assess the …

Intergenerational transmission of the effects of maternal exposure to childhood maltreatment in the USA: a retrospective cohort study

NK Moog, PD Cummings, KL Jackson… - The Lancet Public …, 2023 - thelancet.com
Background Childhood maltreatment is associated with adverse health outcomes and this
risk can be transmitted to the next generation. We aimed to investigate the association …

Nature× nurture: Genetic vulnerabilities interact with physical maltreatment to promote conduct problems

SR Jaffee, A Caspi, TE Moffitt, KA Dodge… - Development and …, 2005 - cambridge.org
Maltreatment places children at risk for psychiatric morbidity, especially conduct problems.
However, not all maltreated children develop conduct problems. We tested whether the …

A genetically informed Registered Report on adverse childhood experiences and mental health

JR Baldwin, HM Sallis, T Schoeler, MJ Taylor… - Nature human …, 2023 - nature.com
Children who experience adversities have an elevated risk of mental health problems.
However, the extent to which adverse childhood experiences (ACEs) cause mental health …

Childhood maltreatment and the structure of common psychiatric disorders

KM Keyes, NR Eaton, RF Krueger… - The British Journal of …, 2012 - cambridge.org
BackgroundPrevious research suggests that various types of childhood maltreatment
frequently co-occur and confer risk for multiple psychiatric diagnoses. This non-specific …

Disentangling the mental health impact of childhood abuse and neglect

CAM Cecil, E Viding, P Fearon, D Glaser… - Child abuse & neglect, 2017 - Elsevier
It is unclear whether maltreatment types exert common or specific effects on mental health.
In the current study, we aimed to systematically characterize the unique, shared and …

Epigenetic signatures of childhood abuse and neglect: Implications for psychiatric vulnerability

CAM Cecil, RG Smith, E Walton, J Mill… - Journal of psychiatric …, 2016 - Elsevier
Childhood maltreatment is a key risk factor for poor mental and physical health. Recently,
variation in epigenetic processes, such as DNA methylation, has emerged as a potential …