Lupus nephritis (LN) is a common manifestation of systemic lupus erythematosus that can
lead to irreversible renal impairment. Although the prognosis of LN has improved …

Despite marked improvements in the survival of patients with severe lupus nephritis over the
past 50 years, the rate of complete clinical remission after immune suppression therapy is< …

Systemic lupus erythematosus is a chronic autoimmune disease characterized by loss of
tolerance against nuclear and cytoplasmic self-antigens, induction of immunity and tissue …

Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disease characterized by
the production of pathogenic immunoglobulins, such as antinuclear and antiphospholipid …

Lupus nephritis is a potentially devastating complication of systemic lupus erythematosus.
Immune cells, cytokines, and epigenetic factors have all been recently implicated in lupus …

Systemic lupus erythematosus (SLE) is a chronic multifactorial autoimmune disease that
affects many organs, including the kidney. Lupus nephritis (LN) is a common manifestation …

Lupus nephritis (LN) is a major cause of morbidity and mortality in patients with systemic
lupus erythematosus. Although the use of aggressive immunosuppression has improved …

Lupus nephritis is a challenging clinical condition for which current therapies are
unsatisfactory with respect to both remission induction and unwanted toxic effects. Despite …

Lupus is no longer an unknown chameleon of medicine. Significant progress has been
made on unraveling the pathogenesis of lupus and lupus nephritis, and how to treat the …

Over the past year, and for the first time ever, the US Food and Drug Administration
approved 2 drugs specifically for the treatment of lupus nephritis (LN). As the lupus …