Schizophrenia is a psychiatric disorder whose pathophysiology is largely unknown. It has a
heritability of 60-80%, much of which is attributable to common risk alleles, suggesting …

Large-scale genomic studies of schizophrenia have identified hundreds of genetic loci
conferring risk to the disorder. This progress offers an important route toward defining the …

Schizophrenia has a heritability of 60–80%, much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …

Genomic studies have identified hundreds of candidate genes near loci associated with risk
for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologs …

Schizophrenia is a complex highly heritable disorder. Genome-wide association studies
(GWAS) have identified multiple loci that influence the risk of developing schizophrenia …

Genome-wide association studies have identified 108 schizophrenia risk loci, but biological
mechanisms for individual loci are largely unknown. Using developmental, genetic and …

Recent large-scale genomic studies have revealed two broad classes of risk alleles for
schizophrenia: a polygenic component of risk mediated through multiple common risk …

By meta-analyzing the whole-exomes of 24,248 cases and 97,322 controls, we implicate
ultra-rare coding variants (URVs) in ten genes as conferring substantial risk for …

Schizophrenia has a heritability of 60-80% 1, much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …