Background Inflammatory bowel diseases (IBD) result from an interaction between genetic
and environmental factors. Preliminary findings suggest that susceptibility genes differ …

Inflammatory bowel disease (IBD) is a chronic relapsing intestinal inflammatory disorder with
unidentified causes. Currently, studies indicate that IBD results from a complex interplay …

The pathogenesis of inflammatory bowel disease (IBD) is not well-understood; however,
increased and persistent intestinal inflammation, due to inappropriate immune responses …

Background There are substantial differences in inflammatory bowel disease (IBD) genetics
depending on the populations examined. We aimed to identify Japanese population-specific …

Background Crohn's disease (CD) and ulcerative colitis (UC) are two major forms of
inflammatory bowel disease (IBD). Meta-analyses of genome-wide association studies …

Twin studies and large-scale population studies have confirmed an increased sibling risk for
both Crohn's disease (CD) and ulcerative colitis (UC). Unlike single gene disorders, CD and …

Epidemiological and clinical studies have suggested that the pathogenesis of inflammatory
bowel disease (IBD) is strongly influenced by genetic predisposition. Beyond the limitations …

The influence of genetics in the etiology of inflammatory bowel disease (IBD) was initially
demonstrated by epidemiological data, including differences in prevalence among different …

A rising trend in the incidence and prevalence of inflammatory bowel disease (IBD) in Asia
has been recognized for the past two decades. It has been postulated that this phenomenon …

Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …