[HTML][HTML] Inflammatory bowel disease: genetics, epigenetics, and pathogenesis

I Loddo, C Romano - Frontiers in immunology, 2015 - frontiersin.org
Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …

Genetics and pathogenesis of inflammatory bowel disease

TC Liu, TS Stappenbeck - Annual Review of Pathology …, 2016 - annualreviews.org
We are currently in an exciting time when our understanding of genetic underpinnings of
inflammatory bowel disease (IBD) has undergone a revolution, based in large part on novel …

Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility

BD Ye, DPB McGovern - Expert review of clinical immunology, 2016 - Taylor & Francis
Epidemiological and clinical studies have suggested that the pathogenesis of inflammatory
bowel disease (IBD) is strongly influenced by genetic predisposition. Beyond the limitations …

[HTML][HTML] From genetics to epigenetics, roles of epigenetics in inflammatory bowel disease

Z Zeng, A Mukherjee, H Zhang - Frontiers in Genetics, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) is a destructive, recurrent, and heterogeneous disease. Its
detailed pathogenesis is still unclear, although available evidence supports that IBD is …

Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics

NT Ventham, NA Kennedy, ER Nimmo, J Satsangi - Gastroenterology, 2013 - Elsevier
In the past decade, there have been fundamental advances in our understanding of genetic
factors that contribute to the inflammatory bowel diseases (IBDs) Crohn's disease and …

Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine

P Goyette, C Labbé, TT Trinh, RJ Xavier… - Annals of …, 2007 - Taylor & Francis
Crohn's disease (CD) and ulcerative colitis (UC), also known as inflammatory bowel
diseases (IBD), are characterized by chronic inflammation of the gastrointestinal tract. IBD is …

[PDF][PDF] A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort

J Hampe, S Schreiber, SH Shaw, KF Lau… - The American journal of …, 1999 - cell.com
Inflammatory bowel disease (IBD) is characterized by a chronic relapsing intestinal
inflammation, typically starting in early adulthood. IBD is subdivided into two subtypes, on …

[HTML][HTML] Inflammatory bowel disease: pathogenesis

YZ Zhang, YY Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is
characterized by chronic relapsing intestinal inflammation. It has been a worldwide health …

The genetic basis of inflammatory bowel disease

R Cooney, D Jewell - Digestive diseases, 2009 - karger.com
Twin studies and large-scale population studies have confirmed an increased sibling risk for
both Crohn's disease (CD) and ulcerative colitis (UC). Unlike single gene disorders, CD and …

[HTML][HTML] Genetic and epigenetic etiology of inflammatory bowel disease: An update

S Jarmakiewicz-Czaja, M Zielińska, A Sokal, R Filip - Genes, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and
remission of the disease. The etiology of IBD is not fully understood. Many studies point to …